2009 年至 2020 年射血分数保留型心力衰竭的全球现状和趋势：文献计量分析。

BACKGROUND: Heart failure with preserved ejection fraction (HFpEF) comprises about 50% of the cases of heart failure (HF), but so far there is no effective treatment strategy. This study used bibliometric methods to analyze the scientific literature on HFpEF in 2009 to 2020, and evaluate the global scientific output of HFpEF research, in order to explore the research status and trends in this field. METHODS: Documents about the HFpEF research published in 2009 to 2020 were retrieved from Science Citation Index Expanded (SCIE) in Web of Science. This study used bibliometrix R-package, VOSviewer, and CiteSpace to conduct the bibliometric analysis. RESULTS: A total of 1971 documents (1508 articles and 283 reviews) were retrieved to construct the local HFpEF literature collection for analysis. The number of annual documents had increased year by year in general, from 24 to 353. Relevant documents were mainly written in English, and mostly focused on the field of "Cardiovascular System Cardiology." USA ranked first in the relevant countries/regions with most documents, and the leading affiliation was Mayo Clin. Shah SJ was the most productive author, while Borlaug BA ranked highest among the local cited authors and G-index. Circulation was the most local cited source, while Eur J Heart Fail published the most documents and was rated as the top source in terms of G-index. "Paulus WJ, 2013, J Am Coll Cardiol" was the top local cited document within the local HFpEF literature collection, while "Owan TE, 2006, New Engl J Med" outside the local HFpEF literature collection was the most local cited reference. The keywords such as "mortality," "dysfunction," "diagnosis," "outcomes," and "diastolic dysfunction" were most frequent, while "hemodynamics," "comorbidity," "myocardial infarction," "inflammation," and "phenotype" indicated research frontiers or emerging trends. Furthermore, this study also found some deeper bibliometric relationships through bibliographic networks. CONCLUSIONS: Due to the multi-dimensional bibliometric analysis, this study shows a wide view of scientific productivity related to HFpEF, and provides valuable guidance for researchers interested in HFpEF, assisting them in understanding the research status, identifying potential collaborators, discovering research hotspots and frontiers, and conducting more in-depth research.

背景：射血分数保留型心力衰竭（HFpEF）约占心力衰竭（HF）病例的 50%，但迄今为止尚无有效的治疗策略。本研究采用文献计量学方法分析了 2009 年至 2020 年 HFpEF 的科学文献，并评估了 HFpEF 研究的全球科学产出，以探讨该领域的研究现状和趋势。

方法：从 Web of Science 中的科学引文索引扩展版（SCIE）中检索到 2009 年至 2020 年发表的关于 HFpEF 研究的文献。本研究使用 bibliometrix R 包、VOSviewer 和 CiteSpace 进行文献计量分析。

结果：共检索到 1971 篇文献（1508 篇文章和 283 篇综述），构建了局部 HFpEF 文献集进行分析。总的来说，每年的文献数量呈逐年递增趋势，从 24 篇增加到 353 篇。相关文献主要用英文撰写，主要集中在“心血管系统心脏病学”领域。美国在相关国家/地区中发文量最多，领先的机构是梅奥诊所。Shah SJ 是最具生产力的作者，而 Borlaug BA 在当地被引作者和 G-指数中排名最高。Circulation 是最受当地引用的来源，而 Eur J Heart Fail 发表的文献最多，在 G-指数方面被评为顶级来源。“Paulus WJ，2013，J Am Coll Cardiol”是局部 HFpEF 文献集中被引最多的文献，而“Owan TE，2006，New Engl J Med”是局部 HFpEF 文献集外被引最多的文献。“死亡率”、“功能障碍”、“诊断”、“结局”和“舒张功能障碍”等关键词出现频率最高，而“血液动力学”、“合并症”、“心肌梗死”、“炎症”和“表型”则表明了研究前沿或新兴趋势。此外，本研究还通过文献计量网络发现了一些更深层次的文献计量关系。

结论：由于多维文献计量分析，本研究展示了与 HFpEF 相关的科学生产力的广泛视角，并为对 HFpEF 感兴趣的研究人员提供了有价值的指导，帮助他们了解研究现状，确定潜在的合作者，发现研究热点和前沿，并进行更深入的研究。