Department of Cardiovascular Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Department of Cardiovascular Diseases, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, China; Shanxi University of Chinese Medicine, Xianyang, Shanxi, China.
Curr Probl Cardiol. 2022 Sep;47(9):101243. doi: 10.1016/j.cpcardiol.2022.101243. Epub 2022 May 8.
Heart Failure with preserved Ejection Fraction (HFpEF) is a heterogeneous disease, which is becoming a worldwide menace. By retrieving the relevant literature of HFpEF from 2000 to 2021, qualitative and quantitative evaluations are carried out to visualize the scientific achievements in this field. The data were from the Web of Science Core Collection database. The bibliometric tool-CiteSpace is used for scientific econometric analysis to understand the development of disciplines and research hotspots in this field. A total of 6318 HFpEF-related research papers were collected by Web of Science Core Collection database from 2000 to 2021, and the number of published papers and citations were in the rising stage. Fund-funded publications accounted for 80.4 percent of total publications, mainly at the national level, with the largest number being funded by the United States Department of Health and Public Services. The number of publications and centrality of the USA ranked first, indicating that the USA is mature in this research field and is in a leading position in the industry, which may benefit from the contributions of scientific research institutions such as Mayo Medical Center, Brigham Women's Hospital, Northwest University and Duke University. Low-income and middle-income countries lag far behind developed countries in terms of health care and scientific research and need to strengthen international cooperation. Bibliometric analysis shows that the main research directions of HFpEF are epidemiology, treatment, and comorbidity research of HFpEF and atrial fibrillation. Chronic microvascular inflammation is the latest research paradigm of HFpEF, especially phosphodiesterase 5 inhibitors.
射血分数保留的心力衰竭（HFpEF）是一种异质性疾病，正在成为全球性的威胁。通过从 2000 年到 2021 年检索 HFpEF 的相关文献，进行定性和定量评估，以可视化该领域的科学成果。数据来自 Web of Science 核心合集数据库。使用文献计量工具 CiteSpace 进行科学计量分析，以了解该领域学科的发展和研究热点。通过 Web of Science 核心合集数据库从 2000 年到 2021 年共收集了 6318 篇 HFpEF 相关研究论文，发表论文数量和引文数量呈上升阶段。受资助的出版物占总出版物的 80.4%，主要来自国家层面，其中美国健康与公众服务部资助的数量最多。出版物数量和中心度排名第一的是美国，这表明美国在该研究领域已经成熟，处于行业领先地位，这可能得益于梅奥医学中心、布莱根妇女医院、西北大学和杜克大学等科研机构的贡献。中低收入国家在医疗保健和科研方面远远落后于发达国家，需要加强国际合作。文献计量分析表明，HFpEF 的主要研究方向是流行病学、HFpEF 和心房颤动的治疗以及合并症研究。慢性微血管炎症是 HFpEF 的最新研究范式，特别是磷酸二酯酶 5 抑制剂。
