Ghisolfi J, Thouvenot J P, Olives J P, Brunerie M, Couvras O
Arch Fr Pediatr. 1986 May;43(5):317-20.
Sodium, potassium and chloride stool content was studied in 107 children aged 1 to 32 months (11 +/- 8 months) presenting with acute diarrhea related to a rotavirus infection (34 cases), to an invasive pathogen (Salmonella or Shigella 14 cases, E. coli 4 cases), or of non-identified etiology (65 cases). The therapeutic protocol was the same in all cases: rehydration for the first 24 hours, progressive realimentation from the second or third day, no drugs being given. An average of 4 stools were analysed for each child (range 2-14), the fecal samples being collected over 2 to 4 consecutive days. Na+ and K+ (n = 366) were assayed by flame photometry and chloride (n = 88) by continuous colorimetry. In the stool samples taken as a whole, without taking into account etiology or day of sampling, the electrolyte concentration (mean +/- SD) was 42 +/- 20 mmol/l for Na+ (range 4-166), 51 +/- 24 mmol/l for K+ (range 5-195), and 24 +/- 11 mmol/l for Cl- (range 4-93). No significant variation of these values was observed according to etiology, duration, severity of the diarrheal syndrome, oral rehydration or nutrition.
对107名年龄在1至32个月(平均11±8个月)的儿童进行了粪便钠、钾和氯含量研究,这些儿童患有与轮状病毒感染相关的急性腹泻(34例)、侵袭性病原体感染(沙门氏菌或志贺氏菌感染14例,大肠杆菌感染4例)或病因不明的急性腹泻(65例)。所有病例的治疗方案相同:头24小时进行补液,从第二天或第三天开始逐步恢复饮食,不使用药物。每个儿童平均分析4次粪便(范围为2至14次),粪便样本连续采集2至4天。采用火焰光度法测定钠和钾(n = 366),采用连续比色法测定氯(n = 88)。在将所有粪便样本作为一个整体进行分析时,不考虑病因或采样日期,电解质浓度(均值±标准差)为:钠42±20 mmol/L(范围4至166),钾51±24 mmol/L(范围5至195),氯24±11 mmol/L(范围4至93)。根据病因、病程、腹泻综合征的严重程度、口服补液或营养情况,未观察到这些值有显著差异。