Suwatano O
King Mongkut Prachomklao Hospital, Phetchaburi, Thailand.
J Med Assoc Thai. 1997 Jan;80(1):26-33.
A prospective epidemiological and clinical study of acute diarrhea in children under 5 years old was done at King Mongkut Prachomklao Hospital in order to provide baseline data for health officers to make a strategic plan to reduce the diarrheal mortality and morbidity, which is one of the mid-decade goals for children. There were 105 cases of acute diarrhea patients admitted to the Pediatric ward between May 1995 and April 1996. Seventy-six per cent of them were in the younger age group (> 1 month-2 years old) while 23.8 per cent were in the older age group (2-5 years old). Causative pathogens were identified in 64 patients (61%). Younger patients had a higher percentage of identifiable pathogens (66.7%) than older patients (44.4%). Rotavirus was the most common pathogen isolated (17.2%). The other common pathogens identified were Eschericia coli (14.1%), Campylobacter jejuni (14.1%), Shigella (12.5%), Entamoeba histolytica (7.8%) and Salmonella (3.1%). Mixed infections were reported in 31.3 per cent of these patients. Clinical presentations and stool characteristics were difficult to distinguish from most of the pathogens. However, Rotavirus was highly suspected if a younger child presented with fever, watery to loose stool with the predominant symptom of vomiting. Mucous, mucous-bloody stool gave a clue to the diagnosis of Shigella and Entamoeba histolytica. Most cases had at least mild to moderate dehydration, so oral rehydration solution (ORS) was successfully given in only 31.4 per cent of patients. Antibiotics were prescribed to 51.4 per cent of patients in this study. Healthcare personnel should emphasize to parents and caretakers about good hygienic behavior to reduce the episodes of diarrhea and the use of ORS every time when their children have diarrheal episodes to reduce the disease severity.
蒙库国王帕乔姆克劳医院对5岁以下儿童急性腹泻进行了一项前瞻性流行病学和临床研究,目的是为卫生官员提供基线数据,以便制定战略计划来降低腹泻死亡率和发病率,这是儿童十年中期目标之一。1995年5月至1996年4月期间,儿科病房收治了105例急性腹泻患者。其中76%为年龄较小的组(>1个月至2岁),23.8%为年龄较大的组(2至5岁)。64例患者(61%)的致病病原体得以确定。年龄较小的患者中可识别病原体的比例(66.7%)高于年龄较大的患者(44.4%)。轮状病毒是分离出的最常见病原体(17.2%)。其他确定的常见病原体为大肠杆菌(14.1%)、空肠弯曲菌(14.1%)、志贺氏菌(12.5%)、溶组织内阿米巴(7.8%)和沙门氏菌(3.1%)。这些患者中有31.3%报告为混合感染。大多数病原体的临床表现和粪便特征难以区分。然而,如果幼儿出现发热、水样便至稀便且主要症状为呕吐,则高度怀疑为轮状病毒感染。黏液便、黏液血便提示志贺氏菌和溶组织内阿米巴的诊断。大多数病例至少有轻度至中度脱水,因此仅31.4%的患者成功给予了口服补液盐(ORS)。本研究中51.4%的患者使用了抗生素。医护人员应向家长和看护人强调良好的卫生行为,以减少腹泻发作次数,并在孩子每次腹泻发作时使用ORS,以减轻疾病严重程度。