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Rapid-CNS: rapid comprehensive adaptive nanopore-sequencing of CNS tumors, a proof-of-concept study.

作者信息

Patel Areeba, Dogan Helin, Payne Alexander, Krause Elena, Sievers Philipp, Schoebe Natalie, Schrimpf Daniel, Blume Christina, Stichel Damian, Holmes Nadine, Euskirchen Philipp, Hench Jürgen, Frank Stephan, Rosenstiel-Goidts Violaine, Ratliff Miriam, Etminan Nima, Unterberg Andreas, Dieterich Christoph, Herold-Mende Christel, Pfister Stefan M, Wick Wolfgang, Loose Matthew, von Deimling Andreas, Sill Martin, Jones David T W, Schlesner Matthias, Sahm Felix

机构信息

Department of Neuropathology, University Hospital Heidelberg, Heidelberg, Germany.

Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 224, 69120, Heidelberg, Germany.

出版信息

Acta Neuropathol. 2022 May;143(5):609-612. doi: 10.1007/s00401-022-02415-6. Epub 2022 Mar 31.

DOI:10.1007/s00401-022-02415-6
PMID:35357562
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9038836/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d746/9038836/8068d18f0f11/401_2022_2415_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d746/9038836/8068d18f0f11/401_2022_2415_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d746/9038836/8068d18f0f11/401_2022_2415_Fig1_HTML.jpg

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Ultrarapid Nanopore Genome Sequencing in a Critical Care Setting.重症监护环境下的超快速纳米孔基因组测序
N Engl J Med. 2022 Feb 17;386(7):700-702. doi: 10.1056/NEJMc2112090. Epub 2022 Jan 12.
3
Targeted long-read sequencing identifies missing disease-causing variation.靶向长读长测序可识别缺失的致病变异。
微生物分子方法对宏基因组研究中使用纳米孔测序进行适应性采样的影响。
Environ Microbiome. 2025 May 5;20(1):47. doi: 10.1186/s40793-025-00704-7.
4
Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors.中枢神经系统肿瘤快速分子谱分析平台的前瞻性多中心验证
Nat Med. 2025 May;31(5):1567-1577. doi: 10.1038/s41591-025-03562-5. Epub 2025 Mar 25.
5
Unraveling the hidden complexity of cancer through long-read sequencing.通过长读长测序揭示癌症隐藏的复杂性。
Genome Res. 2025 Apr 14;35(4):599-620. doi: 10.1101/gr.280041.124.
6
Toward the use of nanopore RNA sequencing technologies in the clinic: challenges and opportunities.迈向纳米孔RNA测序技术在临床中的应用：挑战与机遇
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7
Rapid brain tumor classification from sparse epigenomic data.基于稀疏表观基因组数据的快速脑肿瘤分类
Nat Med. 2025 Mar;31(3):840-848. doi: 10.1038/s41591-024-03435-3. Epub 2025 Feb 28.
8
Explainable artificial intelligence of DNA methylation-based brain tumor diagnostics.基于DNA甲基化的脑肿瘤诊断的可解释人工智能
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