Jain Miten, Olsen Hugh E, Paten Benedict, Akeson Mark
UC Santa Cruz Genomics Institute and Department of Biomolecular Engineering, University of California, Santa Cruz, CA, 95064, USA.
Genome Biol. 2016 Nov 25;17(1):239. doi: 10.1186/s13059-016-1103-0.
Nanopore DNA strand sequencing has emerged as a competitive, portable technology. Reads exceeding 150 kilobases have been achieved, as have in-field detection and analysis of clinical pathogens. We summarize key technical features of the Oxford Nanopore MinION, the dominant platform currently available. We then discuss pioneering applications executed by the genomics community.
纳米孔DNA链测序已成为一项具有竞争力的便携式技术。已实现超过150千碱基的读数，临床病原体的现场检测和分析也已实现。我们总结了目前占主导地位的平台牛津纳米孔MinION的关键技术特征。然后，我们讨论了基因组学界开展的开创性应用。
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