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氯伏胺与多塞平治疗重度抑郁症:一项双盲对照试验。

Clovoxamine and doxepin in major depressive disorder: a double-blind controlled trial.

作者信息

Lodge G J, Freeman H L

出版信息

Br J Psychiatry. 1986 Jun;148:718-21. doi: 10.1192/bjp.148.6.718.

DOI:10.1192/bjp.148.6.718
PMID:3535975
Abstract

Clovoxamine, an inhibitor of neuronal uptake of both serotin and noradrenaline, was compared with doxepin in depressed patients over four weeks. Antidepressant efficacy was comparable for both drugs, but clovoxamine might have a special degree of efficacy for patients with more severe depressive illnesses.

摘要

氯伏胺是一种血清素和去甲肾上腺素神经元摄取抑制剂,在4周时间内,研究人员将其与多塞平在抑郁症患者中进行了比较。两种药物的抗抑郁疗效相当,但氯伏胺对病情更严重的抑郁症患者可能具有一定程度的特殊疗效。

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