Al-Masri Motasem Y, Ashour Intesar Khaleel, Swafta Ashraf, Al-Shunar Sami
Division of Pathology and Medical Laboratory Science, Department of Biomedical Sciences, An-Najah National University, Nablus, West Bank, State of Palestine.
Department of Biology and Biotechnology, An-Najah National University, Nablus, West Bank, State of Palestine.
Can J Infect Dis Med Microbiol. 2022 Mar 22;2022:2812788. doi: 10.1155/2022/2812788. eCollection 2022.
urogenital tract infections are considered a possible cause of infertility worldwide. Genital infections are difficult and impractical to diagnose by culturing or serology. included in this study were , , and . This cross-sectional study aimed to determine the prevalence of , , and genital infections among infertile males and females patients.
This study included 103 patients who visited Al-Shunar Clinic in Nablus city in Palestine and diagnosed with infertility during January 2018 to October 2018. The semen, urine, and/or vaginal swab specimens collected from patients were examined by PCR for detection of , , and .
A total of 57 semen, 37 urine, and 16 vaginal swab specimens were collected. Out of the 110 examined specimens, 35 (31.8%) were PCR positive for at least one , which were 16 (14.6%) , 11 (10%) , and 8 (7.3%) . Significant association were found between infections of and (=0.044) and between and (=0.005) infections. infection was found in significantly (=0.048) higher percentage in males (20.6%) in comparison with females (5.7%). On the other hand, infection rate in females (8.6%) was slightly higher than males (7.4%). was more prevalent in all age groups except for patient's age group 40-50 years old, where was more prevalent. was also more prevalent in all occupation types and among all smokers.
Urogenital infections caused by , , and could be a possible cause of infertility among patients with different age groups, genders, and occupations. Thus, more attention by infertility centers and physicians is required in adopting molecular methods for diagnosis of infections by these microorganisms.
泌尿生殖道感染被认为是全球不孕症的一个可能原因。通过培养或血清学诊断生殖器感染既困难又不切实际。本研究纳入了[具体内容缺失]、[具体内容缺失]和[具体内容缺失]。这项横断面研究旨在确定不孕男性和女性患者中[具体内容缺失]、[具体内容缺失]和[具体内容缺失]生殖器感染的患病率。
本研究纳入了103名于2018年1月至2018年10月期间前往巴勒斯坦纳布卢斯市的Al-Shunar诊所就诊并被诊断为不孕症的患者。从患者采集的精液、尿液和/或阴道拭子标本通过聚合酶链反应（PCR）检测[具体内容缺失]、[具体内容缺失]和[具体内容缺失]。
共采集了57份精液、37份尿液和16份阴道拭子标本。在110份检测标本中，35份（31.8%）至少对一种[具体内容缺失]的PCR检测呈阳性，其中16份（14.6%）为[具体内容缺失]、11份（10%）为[具体内容缺失]、8份（7.3%）为[具体内容缺失]。在[具体内容缺失]和[具体内容缺失]感染之间（P = 0.044）以及[具体内容缺失]和[具体内容缺失]感染之间（P = 0.005）发现了显著关联。[具体内容缺失]感染在男性中的比例（20.6%）显著高于女性（5.7%）（P = 0.048）。另一方面，[具体内容缺失]感染率在女性中（8.6%）略高于男性（7.4%）。除了40 - 五十岁患者年龄组中[具体内容缺失]更普遍外，[具体内容缺失]在所有年龄组中更普遍。[具体内容缺失]在所有职业类型和所有吸烟者中也更普遍。
由[具体内容缺失]、[具体内容缺失]和[具体内容缺失]引起的泌尿生殖道感染可能是不同年龄组、性别和职业患者不孕的一个可能原因。因此，不孕不育中心和医生需要更加关注采用分子方法诊断这些微生物引起的感染。
