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不同近视程度儿童相对周边屈光的比较研究

Comparative Study of Relative Peripheral Refraction in Children With Different Degrees of Myopia.

作者信息

Xiaoli Lu, Xiangyue Zheng, Lihua Lian, Yuting Huang, Chuni Lin, Yujie Xia, Zhao Wang, Xiaoyi Yu

机构信息

Department of Ophthalmology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, China.

First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.

出版信息

Front Med (Lausanne). 2022 Mar 10;9:800653. doi: 10.3389/fmed.2022.800653. eCollection 2022.

DOI:10.3389/fmed.2022.800653
PMID:35360714
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8960133/
Abstract

PURPOSE

To investigate the difference in the retinal refraction difference value (RDV) using multispectral refractive topography (MRT).

METHODS

Ninety myopic participants, who met the enrolment requirements, were examined with an automatic optometer after mydriasis. According to the value of the spherical equivalent (SE), the participants were divided into Emmetropia group (E, +0.5D < SE < -0.5D), Low Myopia (LM, -0.5D < SE ≤ -3D), and Moderate and high Myopia (MM, -3D < SE ≤ -10D). The ocular biological parameters were detected by optical biometrics (Lenstar 900, Switzerland), including axial length (AL), lens thickness (LT), and keratometry (K1, K2). Furthermore, the MRT was used to measure the retinal RDV at three concentric areas, with 15-degree intervals from fovea into 45 degrees (RDV-15, RDV 15-30, and RDV 30-45), and four sectors, including RDV-S (RDV-Superior), RDV-I (RDV-Inferior), RDV-T (RDV-Temporal), and RDV-N (RDV-Nasal).

RESULTS

In the range of RDV-15, there was a significant difference in the value of RDV-15 between Group E (-0.007 ± 0.148) . Group LM (-0.212 ± 0.399), and Group E . Group MM (0.019 ± 0.106) ( < 0.05); In the range of RDV 15-30, there was a significant difference in the value of RDV 15-30 between Group E (0.114 ± 0.219) . Group LM (-0.106 ± 0.332), and Group LM . Group MM (0.177 ± 0.209; < 0.05); In the range of RDV 30-45, there was a significant difference in the value of RDV 30-45 between Group E (0.366 ± 0.339) . Group LM (0.461 ± 0.304), and Group E . Group MM (0.845 ± 0.415; < 0.05); In the RDV-S position, there was a significant difference in the value of RDV-S between Group LM (-0.038 ± 0.636) and Group MM (0.526 ± 0.540) ( < 0.05); In the RDV-I position, there was a significant difference in the value of RDV-I between Group E (0.276 ± 0.530) . Group LM (0.594 ± 0.513), and Group E . Group MM (0.679 ± 0.589; < 0.05). In the RDV-T position, there was no significant difference in the value of RDV-T among the three groups. In the RDV-N position, there was a significant difference in the value of RDV-N between Group E (0.352 ± 0.623) . Group LM (0.464 ± 0.724), and Group E vs. Group MM (1.078 ± 0.627; < 0.05). The RDV analysis in all directions among the three groups showed a significant difference between RDV-S and RDV-I in Group LM ( < 0.05). Moreover, the correlation analysis showed that SE negatively correlated with AL, RDV 30-45, RDV-S, RDV-I, and RDV-N.

CONCLUSIONS

In this study, there was a significant difference in the value of RDV among Group E, Group LM, and Group MM, and the value of RDV in Group MM was the highest on the whole. In the range of RDV 30-45, there was a growing trend with the increase in the degree of myopia among the three groups. Furthermore, the SE negatively correlated with AL, RDV 30-45, RDV-S, RDV-I, and RDV-N.

摘要

目的

使用多光谱屈光地形图（MRT）研究视网膜屈光差值（RDV）的差异。

方法

90名符合入选标准的近视参与者在散瞳后用自动验光仪进行检查。根据等效球镜度（SE）的值，将参与者分为正视组（E，+0.5D < SE < -0.5D）、低度近视组（LM，-0.5D < SE ≤ -3D）和中度及高度近视组（MM，-3D < SE ≤ -10D）。通过光学生物测量法（瑞士Lenstar 900）检测眼部生物学参数，包括眼轴长度（AL）、晶状体厚度（LT）和角膜曲率（K1、K2）。此外，使用MRT在三个同心区域测量视网膜RDV，从中央凹起以15度间隔至45度（RDV - 15、RDV 15 - 30和RDV 30 - 45），以及四个象限，包括RDV - S（RDV - 上方）、RDV - I（RDV - 下方）、RDV - T（RDV - 颞侧）和RDV - N（RDV - 鼻侧）。

结果

在RDV - 15范围内，E组（-0.007 ± 0.148）、LM组（-0.212 ± 0.399）和E组与MM组（0.019 ± 0.106）之间的RDV - 15值存在显著差异（P < 0.05）；在RDV 15 - 30范围内，E组（0.114 ± 0.219）、LM组（-0.106 ± 0.332）和LM组与MM组（0.177 ± 0.209；P < 0.05）之间的RDV 15 - 30值存在显著差异；在RDV 30 - 45范围内，E组（0.366 ± 0.339）、LM组（0.461 ± 0.304）和E组与MM组（0.845 ± 0.415；P < 0.05）之间的RDV 30 - 45值存在显著差异；在RDV - S位置，LM组（-0.038 ± 0.636）和MM组（0.526 ± 0.540）之间的RDV - S值存在显著差异（P < 0.05）；在RDV - I位置，E组（0.276 ± 0.530）、LM组（0.594 ± 0.513）和E组与MM组（0.679 ± 0.589；P < 0.05）之间的RDV - I值存在显著差异。在RDV - T位置，三组之间的RDV - T值无显著差异。在RDV - N位置，E组（0.352 ± 0.623）、LM组（0.464 ± 0.724）和E组与MM组（1.078 ± 0.627；P < 0.05）之间的RDV - N值存在显著差异。三组在所有方向上的RDV分析显示，LM组中RDV - S和RDV - I之间存在显著差异（P < 0.05）。此外，相关性分析显示，SE与AL、RDV 30 - 45、RDV - S、RDV - I和RDV - N呈负相关。

结论

在本研究中，E组、LM组和MM组之间的RDV值存在显著差异，总体上MM组的RDV值最高。在RDV 30 - 45范围内，三组中随着近视度数增加有上升趋势。此外，SE与AL、RDV 30 - 45、RDV - S

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a0/8960133/a392a55024ae/fmed-09-800653-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a0/8960133/a9736822880f/fmed-09-800653-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a0/8960133/ff2328b7c32f/fmed-09-800653-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a0/8960133/f0e23bd9913f/fmed-09-800653-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a0/8960133/a392a55024ae/fmed-09-800653-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a0/8960133/a9736822880f/fmed-09-800653-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a0/8960133/ff2328b7c32f/fmed-09-800653-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a0/8960133/f0e23bd9913f/fmed-09-800653-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03a0/8960133/a392a55024ae/fmed-09-800653-g0006.jpg

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