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五个欧洲儿科急诊部的实践差异:一项前瞻性观察研究。

Practice variation across five European paediatric emergency departments: a prospective observational study.

机构信息

Willem-Alexander Children's Hospital, department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.

Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam University Medical Centers, Amstersdam, Netherlands.

出版信息

BMJ Open. 2022 Mar 31;12(3):e053382. doi: 10.1136/bmjopen-2021-053382.

Abstract

OBJECTIVES

To compare paediatric healthcare practice variation among five European emergency departments (EDs) by analysing variability in decisions about diagnostic testing, treatment and admission.

DESIGN AND POPULATION

Consecutive paediatric visits in five European EDs in four countries (Austria, Netherlands, Portugal, UK) were prospectively collected during a study period of 9-36 months (2012-2015).

PRIMARY OUTCOME MEASURES

Practice variation was studied for the following management measures: lab testing, imaging, administration of intravenous medication and patient disposition after assessment at the ED.

ANALYSIS

Multivariable logistic regression was used to adjust for general patient characteristics and markers of disease severity. To assess whether ED was significantly associated with management, the goodness-of-fit of regression models based on all variables with and without ED as explanatory variable was compared. Management measures were analysed across different categories of presenting complaints.

RESULTS

Data from 111 922 children were included, with a median age of 4 years (IQR 1.7-9.4). There were large differences in frequencies of Manchester Triage System (MTS) urgency and selected MTS presentational flow charts. ED was a significant covariate for management measures. The variability in management among EDs was fairly consistent across different presenting complaints after adjustment for confounders. Adjusted OR (aOR) for laboratory testing were consistently higher in one hospital while aOR for imaging were consistently higher in another hospital. Iv administration of medication and fluids and admission was significantly more likely in two other hospitals, compared with others, for most presenting complaints.

CONCLUSIONS

Distinctive hospital-specific patterns in variability of management could be observed in these five paediatric EDs, which were consistent across different groups of clinical presentations. This could indicate fundamental differences in paediatric healthcare practice, influenced by differences in factors such as organisation of primary care, diagnostic facilities and available beds, professional culture and patient expectations.

摘要

目的

通过分析诊断检测、治疗和入院决策的变异性,比较欧洲五家急诊科(ED)的儿科医疗实践差异。

设计和人群

2012-2015 年期间,在四个国家(奥地利、荷兰、葡萄牙、英国)的五家欧洲 ED 中连续前瞻性收集儿科就诊。

主要结局测量

研究了以下管理措施的实践差异:实验室检测、影像学、静脉药物管理和 ED 评估后患者处置。

分析

多变量逻辑回归用于调整一般患者特征和疾病严重程度标志物。为了评估 ED 是否与管理显著相关,比较了基于所有变量和不包含 ED 作为解释变量的回归模型的拟合优度。管理措施按不同的就诊症状类别进行分析。

结果

共纳入 111922 名儿童的数据,中位年龄为 4 岁(IQR 1.7-9.4)。曼彻斯特分诊系统(MTS)紧急程度和选定的 MTS 呈现流程图的频率存在很大差异。ED 是管理措施的显著协变量。在调整混杂因素后,ED 之间的管理差异在不同的就诊症状中相当一致。经过调整后,一家医院的实验室检测的调整比值比(aOR)始终较高,而另一家医院的影像学检查的 aOR 始终较高。与其他医院相比,对于大多数就诊症状,两家医院更有可能给予静脉药物和液体输注治疗和入院。

结论

在这五家儿科 ED 中可以观察到管理变异性的独特的医院特异性模式,这些模式在不同的临床表现组中是一致的。这可能表明儿科医疗实践存在根本差异,这些差异受到组织初级保健、诊断设施和可用床位、专业文化和患者期望等因素的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b5/8971764/5637f0d27c32/bmjopen-2021-053382f01.jpg

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