Department of General Paediatrics, Erasmus MC-Sophia Children's Hospital, University Medical Centre Rotterdam, Rotterdam, The Netherlands.
Department of Paediatrics and Adolescent Medicine, Medical University Vienna, Vienna, Austria.
PLoS One. 2021 May 5;16(5):e0251046. doi: 10.1371/journal.pone.0251046. eCollection 2021.
Our aim was to describe variability in resource use and hospitalization in children presenting with shortness of breath to different European Emergency Departments (EDs) and to explore possible explanations for variability.
The TrIAGE project, a prospective observational study based on electronic health record data.
Consecutive paediatric emergency department visits for shortness of breath in five European hospitals in four countries (Austria, Netherlands, Portugal, United Kingdom) during a study period of 9-36 months (2012-2014).
We assessed diversity between EDs regarding resource use (diagnostic tests, therapy) and hospital admission using multivariable logistic regression analyses adjusting for potential confounding variables.
In total, 13,552 children were included. Of those, 7,379 were categorized as immediate/very urgent, ranging from 13-80% in the participating hospitals. Laboratory tests and X-rays were performed in 8-33% of the cases and 21-61% was treated with inhalation medication. Admission rates varied between 8-47% and PICU admission rates varied between 0.1-9%. Patient characteristics and markers of disease severity (age, sex, comorbidity, urgency, vital signs) could explain part of the observed variability in resource use and hospitalization. However, after adjusting for these characteristics, we still observed substantial variability between settings.
European EDs differ substantially regarding the resource use and hospitalization in children with shortness of breath, even when adjusting for patient characteristics. Possible explanations for this variability might be unmeasured patient characteristics such as underlying disease, differences in guideline use and adherence or different local practice patterns.
本研究旨在描述不同欧洲急诊部(ED)接诊的呼吸急促患儿资源使用和住院情况的差异,并探讨差异的可能解释。
TrIAGE 项目,一项基于电子健康记录数据的前瞻性观察性研究。
2012-2014 年期间,在四个国家(奥地利、荷兰、葡萄牙、英国)的五家欧洲医院,对连续出现呼吸急促的儿科急诊就诊患者进行研究。
使用多变量逻辑回归分析评估 ED 之间资源使用(诊断性检查、治疗)和住院的差异,调整潜在混杂变量。
共纳入 13552 例患儿,其中 7379 例被归类为紧急/非常紧急,在参与医院中占比 13%-80%。8%-33%的病例进行了实验室检查和 X 光检查,21%-61%的患儿接受了吸入药物治疗。住院率在 8%-47%之间,PICU 住院率在 0.1%-9%之间。患者特征和疾病严重程度标志物(年龄、性别、合并症、紧急程度、生命体征)可以解释资源使用和住院情况观察到的部分差异。然而,在调整这些特征后,我们仍然观察到不同设置之间存在实质性差异。
即使调整了患者特征,欧洲 ED 之间在呼吸急促患儿的资源使用和住院方面存在显著差异。这种差异的可能解释可能是未测量的患者特征,如潜在疾病、指南使用和依从性的差异,或不同的局部实践模式。