Department of Chemistry, Seoul National University, Seoul, Korea.
Research Institute of Basic Sciences, Seoul National University, Seoul, Korea.
Plant Signal Behav. 2022 Dec 31;17(1):2050095. doi: 10.1080/15592324.2022.2050095.
WUSCHEL-RELATED HOMEOBOX 5 (WOX5) is a member of the WUSCHEL (WUS) homeodomain transcription factor family. is expressed mainly in the quiescent center (QC) and confers stem cell identity in the root apical meristem (RAM). Consistent with the role of in repressing root meristem development, we found that ectopic expression of disrupted shoot development by repressing shoot-related genes, such as (). Our findings suggest that WOX5 and WUS potentially confer different tissue identities and specify RAM and SAM, respectively.
WUSCHEL-RELATED HOMEOBOX 5（WOX5）是 WUSCHEL（WUS）同源结构域转录因子家族的成员。WOX5 主要在静止中心（QC）表达，并赋予根顶端分生组织（RAM）中的干细胞特性。与 在抑制根分生组织发育中的作用一致，我们发现 的异位表达通过抑制与芽相关的基因（如 （））来破坏芽的发育。我们的研究结果表明，WOX5 和 WUS 可能分别赋予不同的组织特性，并分别指定 RAM 和 SAM。
