Emory University, Atlanta, Georgia, United States of America.
Children's Healthcare of Atlanta, 2015 Upper Gate Drive NE, 30322, Atlanta, Georgia, United States of America.
AIDS Behav. 2022 Sep;26(9):3131-3138. doi: 10.1007/s10461-022-03650-4. Epub 2022 Apr 1.
We created a transition readiness score for adolescents with perinatally-acquired HIV as they transition from pediatric to adult care. Of the 199 adolescents who transitioned to adult care, 84 (42%) had viral suppression (< 200 copies/ml) one year after transition. Adolescents on first-line ART, with documented HIV status disclosure, and higher rating on the HIV Adolescent Readiness to Transition Scale had significantly higher odds of viral suppression after transition. Conversely, females, those with older age at ART initiation, and those with prior alcohol use had significantly lower odds of viral suppression after transition. Using these data, we created a transition readiness score organized into low, intermediate, and high levels of transition readiness. This transition readiness score can be used to identify adolescents who are likely ready to transition to adult care and identify additional areas for intervention to improve the likelihood of successful transition for those with lower transition readiness scores.
我们为接受过围产期 HIV 感染治疗的青少年创建了一个过渡准备评分，以便他们从儿科过渡到成人护理。在 199 名过渡到成人护理的青少年中，有 84 名（42%）在过渡后一年达到了病毒抑制（<200 拷贝/ml）。接受一线抗逆转录病毒治疗、已记录 HIV 状况披露且 HIV 青少年过渡准备量表评分较高的青少年在过渡后病毒抑制的可能性显著更高。相反，女性、抗逆转录病毒治疗起始年龄较大的青少年以及有既往饮酒史的青少年在过渡后病毒抑制的可能性显著较低。我们利用这些数据创建了一个过渡准备评分，将其分为低、中、高三个过渡准备水平。这个过渡准备评分可以用来识别那些可能已经准备好过渡到成人护理的青少年，并确定额外的干预领域，以提高那些过渡准备评分较低的青少年成功过渡的可能性。
