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南非青少年从儿科艾滋病护理向成人艾滋病护理的过渡:一项政策审查。

Transition of adolescents from paediatric to adult HIV care in South Africa: A policy review.

作者信息

Petinger Charné, Crowley Talitha, van Wyk Brian

机构信息

School of Public Health, Faculty of Community and Health Sciences, University of the Western Cape, Cape Town, South Africa.

School of Nursing, Faculty of Community and Health Sciences, University of the Western Cape, Cape Town, South Africa.

出版信息

South Afr J HIV Med. 2025 Apr 2;26(1):1674. doi: 10.4102/sajhivmed.v26i1.1674. eCollection 2025.

Abstract

The successful roll-out and improved delivery of antiretroviral therapy (ART) services has led to paediatric HIV patients surviving to reach adolescence. Adolescents living with HIV (ALHIV) are challenged when transitioning to adult HIV care programmes where they must negotiate new care pathways, changes in healthcare providers and self-manage their chronic condition, in addition to dealing with the psychological and physiological developmental changes of adolescence. The transition process needs to be well guided, to ensure that ALHIV on ART maintain optimal adherence and remain engaged in care. Viral suppression and retention in care are significantly lower for older adolescents (15-19 years) compared to children and younger adolescents under 15 years - coinciding with the post-transition period. Comprehensive and structured transition protocols may have a significant impact on positive health outcomes. In sub-Saharan Africa, there is a dearth of policies and implementation guidelines for ALHIV who are transitioning to adult HIV care. The current review reports on policies and guidelines for transitioning ALHIV to adult HIV care in South Africa. Eight policies were identified, which were developed at global ( = 2), national ( = 2) and provincial levels ( = 1), and guided implementation ( = 3). Current national and provincial policies provide guidance on when to transition a patient clinically to facilitate the switch to adult ART regimens. Although global policies and implementation guidelines emphasise specific and comprehensive care for ALHIV on ART, these are not carried over to national and provincial policies in South Africa. Further development of policies is required to guide comprehensive, adolescent-friendly transition processes for ALHIV on ART in South Africa.

摘要

抗逆转录病毒疗法(ART)服务的成功推广和改善,使得感染艾滋病毒的儿童患者存活至青春期。感染艾滋病毒的青少年(ALHIV)在向成人艾滋病毒护理项目过渡时面临挑战,他们不仅要应对青春期的心理和生理发育变化,还必须协商新的护理途径、更换医疗服务提供者并自我管理慢性病。这一过渡过程需要得到良好的引导,以确保接受抗逆转录病毒治疗的感染艾滋病毒青少年保持最佳依从性并持续接受护理。与15岁以下的儿童和青少年相比,年龄较大的青少年(15 - 19岁)在过渡后期的病毒抑制率和护理留存率明显较低。全面且结构化的过渡方案可能对积极的健康结果产生重大影响。在撒哈拉以南非洲,缺乏针对向成人艾滋病毒护理过渡的感染艾滋病毒青少年的政策和实施指南。本综述报告了南非关于感染艾滋病毒青少年向成人艾滋病毒护理过渡的政策和指南。共确定了八项政策,分别在全球(= 2)、国家(= 2)和省级层面(= 1)制定,并指导实施(= 3)。当前的国家和省级政策为临床何时过渡患者以促进转用成人抗逆转录病毒治疗方案提供了指导。尽管全球政策和实施指南强调为接受抗逆转录病毒治疗的感染艾滋病毒青少年提供具体且全面的护理,但这些内容并未延续到南非的国家和省级政策中。南非需要进一步制定政策,以指导针对接受抗逆转录病毒治疗的感染艾滋病毒青少年的全面、适合青少年的过渡过程。

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