用曲恩汀治疗镍皮炎。

Treatment of nickel dermatitis with Trientine.

作者信息

Burrows D, Rogers S, Beck M, Kellett J, McMaster D, Merrett D, Eedy D J

出版信息

Contact Dermatitis. 1986 Aug;15(2):55-7. doi: 10.1111/j.1600-0536.1986.tb01275.x.

DOI:10.1111/j.1600-0536.1986.tb01275.x

Abstract

23 nickel-sensitive patients with hand eczema were treated with Trientine 300 mg daily and a placebo in a double-blind, crossover trial. No significant improvement occurred in the hand eczema. A surprising finding was that there was no detectable increase in urinary nickel excretion, in contrast to animal studies.

摘要

23名对镍敏感的手部湿疹患者在一项双盲交叉试验中，每天接受300毫克曲恩汀治疗，并服用安慰剂。手部湿疹没有明显改善。一个惊人的发现是，与动物研究相反，尿镍排泄没有可检测到的增加。