Students' Scientific Society at the Pathophysiology Unit, Department of Pathophysiology, Medical Faculty in Katowice, The Medical University of Silesia, Katowice Poland.
Eur Rev Med Pharmacol Sci. 2022 Mar;26(6):2171-2178. doi: 10.26355/eurrev_202203_28365.
Several receptors for the angiotensin-converting enzyme 2 (ACE2), essential for the penetration of SARS-CoV-2 into cells, are located in the tissues of the endocrine glands. Therefore, it has been suggested that SARS-CoV-2 infection results in the development of hormonal disturbances. To date, several cases of endocrine disturbances related to the dysfunction of all endocrine glands during and after SARS-CoV-2 infection have been described. In this review, we discuss the endocrine system disturbances in patients with COVID-19 and post-COVID-19 syndrome. Based on the case reports described in the literature, patients with COVID-19 may develop endocrine disturbances that are immediately life-threatening. In addition, patients with post-COVID-19 syndrome may develop chronic endocrine disturbances. In summary, the diagnostics of endocrine system disturbances based on clinical symptoms should be taken into account in both patients with COVID-19 and post-COVID-19 syndrome.
几种血管紧张素转换酶 2（ACE2）受体，对于 SARS-CoV-2 进入细胞至关重要，位于内分泌腺的组织中。因此，有人认为 SARS-CoV-2 感染会导致激素紊乱。迄今为止，已经描述了几种与 SARS-CoV-2 感染期间和之后所有内分泌腺功能障碍相关的内分泌紊乱的病例。在这篇综述中，我们讨论了 COVID-19 患者和 COVID-19 后综合征患者的内分泌系统紊乱。基于文献中描述的病例报告，COVID-19 患者可能会出现立即危及生命的内分泌紊乱。此外，COVID-19 后综合征患者可能会出现慢性内分泌紊乱。总之，COVID-19 和 COVID-19 后综合征患者均应考虑基于临床症状的内分泌系统紊乱诊断。
