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圆扫描 OCT 信号的射频特性。

RF properties of circular-ranging OCT signals.

出版信息

Opt Lett. 2022 Apr 1;47(7):1903-1906. doi: 10.1364/OL.450318.

DOI:10.1364/OL.450318
PMID:35363765
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9027934/
Abstract

Circular-ranging optical coherence tomography (CR-OCT) systems that use a time-stepped frequency comb source generate interference fringe signals that are more complex than those of a conventional swept-source OCT system. Here, we define a common terminology for describing these signals, and we develop a mathematical framework that relates the radio-frequency (RF) properties of these fringe signals to the parameters of the frequency comb source. With this framework, we highlight non-intuitive mechanisms whereby the design of the frequency comb source can affect imaging performance. We show, for example, that amplitude-pulsed time-stepped frequency comb sources have a sensitivity advantage over constant power time-stepped frequency comb sources. More broadly, this framework and associated terminology provide a foundation on which to design and optimize time-stepped frequency comb sources and systems.

摘要

环形扫描光学相干断层成像(CR-OCT)系统使用时间步进频率梳源产生的干涉条纹信号比传统的扫频源 OCT 系统更为复杂。在这里,我们为描述这些信号定义了一个通用术语,并开发了一个数学框架,将这些条纹信号的射频(RF)特性与频率梳源的参数联系起来。利用这个框架,我们突出了频率梳源的设计如何影响成像性能的非直观机制。例如,我们表明,与恒定功率时间步进频率梳源相比,幅度脉冲时间步进频率梳源具有灵敏度优势。更广泛地说,这个框架和相关术语为设计和优化时间步进频率梳源和系统提供了基础。

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本文引用的文献

1
Soliton microcomb based spectral domain optical coherence tomography.基于孤子微梳的光谱域光学相干断层扫描。
Nat Commun. 2021 Jan 18;12(1):427. doi: 10.1038/s41467-020-20404-9.
2
Stepped frequency comb generation based on electro-optic phase-code mode-locking for moderate-speed circular-ranging OCT.基于电光相位编码锁模的步进频率梳生成用于中速圆周扫描光学相干断层扫描。
Biomed Opt Express. 2020 Jun 8;11(7):3534-3542. doi: 10.1364/BOE.392359. eCollection 2020 Jul 1.
3
Optical frequency combs: Coherently uniting the electromagnetic spectrum.光学频率梳:协调统一电磁波谱
Science. 2020 Jul 17;369(6501). doi: 10.1126/science.aay3676.
4
Resolving absolute depth in circular-ranging optical coherence tomography by using a degenerate frequency comb.利用简并频率梳解决圆域测距光学相干断层扫描中的绝对深度问题。
Opt Lett. 2020 Jan 15;45(2):371-374. doi: 10.1364/ol.379968.
5
Extended Coherence Length and Depth Ranging Using a Fourier-Domain Mode-Locked Frequency Comb and Circular Interferometric Ranging.使用傅里叶域锁模频率梳和圆形干涉测距实现扩展相干长度和深度测距
Phys Rev Appl. 2019 Jan;11(1). doi: 10.1103/physrevapplied.11.014018. Epub 2019 Jan 9.
6
Stable multi-megahertz circular-ranging optical coherence tomography at 1.3 µm.1.3微米处的稳定多兆赫兹环形光学相干断层扫描技术
Biomed Opt Express. 2019 Dec 9;11(1):174-185. doi: 10.1364/BOE.11.000174. eCollection 2020 Jan 1.
7
High-speed optical coherence tomography by circular interferometric ranging.基于环形干涉测距的高速光学相干断层扫描术。
Nat Photonics. 2018;12:111-116. doi: 10.1038/s41566-017-0088-x. Epub 2018 Jan 29.
8
A rapid, dispersion-based wavelength-stepped and wavelength-swept laser for optical coherence tomography.一种用于光学相干断层扫描的基于色散的快速波长步进和波长扫描激光器。
Opt Express. 2014 Feb 10;22(3):3414-24. doi: 10.1364/OE.22.003414.
9
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10
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Opt Express. 2009 Nov 9;17(23):21257-70. doi: 10.1364/OE.17.021257.