Zhang Yuan, Li Shelly-Anne, Yepes-Nuñez Juan Jose, Morgan Rebecca L, Pardo-Hernandez Hector, Alonso Coello Pablo, Ren Melody, Mirza Reza D, Guyatt Gordon H, Schünemann Holger J
Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada; McMaster GRADE Centre, McMaster University, Hamilton, Ontario, Canada; Michael G DeGroote Cochrane Canada Centre, McMaster University, Hamilton, Ontario, Canada.
Lawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
J Clin Epidemiol. 2022 Jul;147:60-68. doi: 10.1016/j.jclinepi.2022.03.007. Epub 2022 Mar 29.
We conceptualize patient values and preferences as the relative importance of health outcomes (RIO) which are often obtained through utility elicitation research. A transparent and structured approach to present synthesized RIO evidence and the certainty of this evidence is needed. This study aims to adapt the summary of findings (SoF) table to describe the RIO.
We performed three interactive workshops with a protype version of the SoF table for RIO, evidence adapted from the SoF table for intervention effects. We then tested the new format through semi-structured interviews with professionals who interpret RIO evidence (e.g., systematic review authors and guideline developers).
We adapted the SoF table for the presentation of RIO evidence. This SoF table may be easy to use, but bears one risk: some participants misunderstood the utility information and the variability around the RIO. We added a visual analogue scale to clarify the concept of utilities.
Through a multi-stage process including brainstorming sessions and interviews, we adapted the SoF table to present RIO evidence. This table may enhance understanding of evidence synthesis of values and preferences, facilitating the incorporation of this type of evidence in decision-making.
我们将患者价值观和偏好概念化为健康结果的相对重要性（RIO），这通常是通过效用诱导研究获得的。需要一种透明且结构化的方法来呈现综合的RIO证据及其证据的确定性。本研究旨在调整结果总结（SoF）表以描述RIO。
我们使用针对RIO的SoF表原型版本进行了三次互动研讨会，证据改编自干预效果的SoF表。然后，我们通过对解读RIO证据的专业人员（如系统评价作者和指南制定者）进行半结构化访谈来测试新格式。
我们调整了SoF表以呈现RIO证据。这个SoF表可能易于使用，但存在一个风险：一些参与者误解了效用信息以及RIO周围的变异性。我们添加了视觉模拟量表以阐明效用的概念。
通过包括头脑风暴会议和访谈在内的多阶段过程，我们调整了SoF表以呈现RIO证据。该表可能会增强对价值观和偏好证据综合的理解，有助于将这类证据纳入决策过程。
