康氏立克次体亚种感染：来自伊朗东南部的一个病例报告。

Rickettsia conorii subsp. israelensis infection: a case report from southeast Iran.

机构信息

Department of Epidemiology and Biostatics, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Tehran, Iran.

National Reference Laboratory for Plague, Tularemia and Q Fever, Research Centre for Emerging and Reemerging Infectious Diseases, Pasteur Institute of Iran, Akanlu, KabudarAhang, Hamadan, Iran.

出版信息

BMC Infect Dis. 2022 Apr 1;22(1):320. doi: 10.1186/s12879-022-07291-9.

DOI:10.1186/s12879-022-07291-9

PMID:35365079

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8974134/

Abstract

BACKGROUND

Mediterranean spotted fever (MSF) is a zoonotic and vector-borne disease caused by Rickettsia conorii. We report a case (36 year-old-woman) of MSF caused by Rickettsia conorii from Iran.

CASE PRESENTATION

In September 2019, the patient was admitted to the hospital in Kerman province with flu-like symptoms and maculopapular lesions. According to the laboratory results, thrombocytopenia, elevated liver enzymes, and cardiac enzymes were observed. Skin biopsy was examined for Crimean-Congo Hemorrhagic Fever (CCHF) and MSF using the Real-Time-PCR and ELISA method. Finally, the sample was positive for Rickettsia conorii subsp. israelensis and treated with doxycycline and completely recovered.

CONCLUSIONS

This study showed that MSF could be present in Iran. Therefore, identifying endemic areas in Iran for this disease should be on the agenda.

摘要

背景

地中海斑疹热（MSF）是一种由恙虫病东方体引起的人畜共患病和媒介传播疾病。我们报告了一例来自伊朗的由恙虫病东方体引起的 MSF（36 岁女性）病例。

病例介绍

2019 年 9 月，该患者以流感样症状和斑丘疹入院至克尔曼省医院。根据实验室结果，观察到血小板减少、肝酶和心肌酶升高。使用实时-PCR 和 ELISA 法对皮肤活检进行了克里米亚-刚果出血热（CCHF）和 MSF 的检查。最后，该样本对恙虫病东方体亚种以色列氏菌呈阳性，并使用多西环素进行治疗，患者完全康复。