Celle G, Savarino V, Biggi E, Mansi C, Ceppa P, Cicio G R, Arcuri V
Gastroenterol Clin Biol. 1986 Aug-Sep;10(8-9):545-8.
One hundred fine-needle aspirations (45 percutaneous ultrasonically-guided and 55 intraoperative) were performed in 82 patients suspected of having pancreatic cancer, in order to evaluate the contribution of cytologic data to definitive diagnosis of this tumor. The overall success rate of both cytologic methods was 90.6 p. 100 in our 64 patients who were histologically proved to have pancreatic cancer. Sensitivity was 77.4 p. 100 with percutaneous and 75.5 p. 100 with intraoperative aspirations. In all 18 cases with the final diagnosis of chronic pancreatitis results of both techniques were negative. Neither relevant morbidity nor mortality were recorded in any of the 82 patients. These cytologic studies are at present reliable, rapid, highly cost-effective (especially percutaneous aspiration) and most important, safer than histologic examinations. We believe that fine-needle aspiration cytology has gained a primary role in the diagnostic process of pancreatic carcinoma. Therefore the old view of considering examination of cytologic material only as a screening procedure should be abandoned.
为了评估细胞学数据对胰腺癌确诊的贡献，对82例疑似患有胰腺癌的患者进行了100次细针穿刺抽吸（45次经皮超声引导下穿刺和55次术中穿刺）。在我们64例经组织学证实患有胰腺癌的患者中，两种细胞学方法的总体成功率为90.6%。经皮穿刺抽吸的敏感性为77.4%，术中穿刺抽吸的敏感性为75.5%。在最终诊断为慢性胰腺炎的所有18例病例中，两种技术的结果均为阴性。82例患者中均未记录到相关的发病率或死亡率。这些细胞学研究目前是可靠、快速、高性价比的（尤其是经皮穿刺抽吸），最重要的是，比组织学检查更安全。我们认为细针穿刺抽吸细胞学在胰腺癌的诊断过程中已发挥主要作用。因此，应摒弃仅将细胞学材料检查视为筛查程序的旧观念。
