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Risk of Substance Use Disorder and Its Associations With Comorbidities and Psychotropic Agents in Patients With Autism.自闭症患者物质使用障碍风险及其与共病和精神药物的关联。
JAMA Pediatr. 2021 Feb 1;175(2):e205371. doi: 10.1001/jamapediatrics.2020.5371.
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Autism Spectrum Disorder and the Risk of Substance Use Disorder: A Call for Targeted Screening and Prevention in Adolescents.自闭症谱系障碍与物质使用障碍风险:呼吁对青少年进行针对性筛查与预防
JAMA Pediatr. 2021 Feb 1;175(2):e205376. doi: 10.1001/jamapediatrics.2020.5376.
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United States Medicaid home and community-based services for people with intellectual and developmental disabilities: A scoping review.美国针对智障和发育障碍人士的医疗补助居家和社区服务:范围综述。
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Utilization of treatment by Medicaid enrollees with opioid use disorder and co-occurring substance use disorders.美沙酮药物滥用者和共病物质使用障碍者的医疗补助治疗利用情况。
Drug Alcohol Depend. 2020 Dec 1;217:108261. doi: 10.1016/j.drugalcdep.2020.108261. Epub 2020 Aug 28.
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Services for Adults With Autism Spectrum Disorder: a Systems Perspective.成人自闭症谱系障碍服务:系统视角。
Curr Psychiatry Rep. 2020 Feb 5;22(3):13. doi: 10.1007/s11920-020-1136-7.
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Considerations for Treating Young People With Comorbid Autism Spectrum Disorder and Substance Use Disorder.考虑治疗同时患有自闭症谱系障碍和物质使用障碍的年轻人。
J Am Acad Child Adolesc Psychiatry. 2019 Dec;58(12):1139-1141. doi: 10.1016/j.jaac.2019.08.467.
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Prevalence and Trends of Developmental Disabilities among Children in the United States: 2009-2017.美国儿童发育障碍的患病率和趋势:2009-2017 年。
Pediatrics. 2019 Oct;144(4). doi: 10.1542/peds.2019-0811.
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Association Between Parental Medical Claims for Opioid Prescriptions and Risk of Suicide Attempt by Their Children.父母医疗报销阿片类药物处方与子女自杀未遂风险的关联。
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Treating Patients With Co-occurring Autism Spectrum Disorder and Substance Use Disorder: A Clinical Explorative Study.治疗同时患有自闭症谱系障碍和物质使用障碍的患者:一项临床探索性研究。
Subst Abuse. 2019 Apr 17;13:1178221819843291. doi: 10.1177/1178221819843291. eCollection 2019.
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Prescription opioid behaviors among adults with and without disabilities - United States, 2015-2016.成年人有无残疾者处方阿片类药物使用行为 - 美国,2015-2016 年。
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全国范围内的医疗补助受助人(自闭症谱系或智力残疾)物质使用障碍情况概况。

A national profile of substance use disorder among Medicaid enrollees on the autism spectrum or with intellectual disability.

机构信息

A.J. Drexel Autism Institute, Drexel University, Philadelphia, PA 3020 Market Street, Suite 560, Philadelphia, PA 19104, USA.

School of Social Policy and Practice, University of Pennsylvania, Philadelphia. 3535 Market St., 3rd Floor, Philadelphia, PA 19104, USA.

出版信息

Disabil Health J. 2022 Jun;15(2S):101289. doi: 10.1016/j.dhjo.2022.101289. Epub 2022 Mar 7.

DOI:10.1016/j.dhjo.2022.101289
PMID:35367189
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9232987/
Abstract

BACKGROUND

Recent research has questioned the assumption that people with intellectual disability (ID) or autism spectrum disorder (ASD) are less at risk of substance use disorders (SUDs). Overall, little is known about SUDs among people with intellectual and developmental disabilities (/IDDs).

OBJECTIVE

This study aimed to estimate prevalence of SUD among Medicaid enrollees with ASD, ID, or ASD + ID; characterize these groups and types of SUDs; and identify risk of SUD by demographic and clinical characteristics within groups.

METHODS

We used 2008-2012 national Medicaid data to identify enrollees with ASD, ID, ASD + ID and a sample without ASD/ID and identified SUDs within these individuals. We used descriptive statistics to characterize enrollee groups and types of SUDs, calculated SUD prevalence, and used modified Poisson regression to examine adjusted relative risk of SUD within disability groups.

RESULTS

SUD prevalence increased yearly across disability groups to 1-2.2%, increasing most quickly among those with ASD. Alcohol abuse was the most common SUD among those with ID-only (57%) versus cannabis abuse among the ASD-only group (41%). Risk of SUD was higher among those with co-occurring psychiatric disorders - notably, depression.

CONCLUSIONS

Results highlight increasing prevalence of SUD among Medicaid enrollees with ASD-only and ASD + ID and higher risk of SUD among those with depression and other psychiatric disorders. Understanding access to screening, diagnosis and treatment of SUD among people with I/DDs is a highly important question for future research.

摘要

背景

最近的研究对智力障碍(ID)或自闭症谱系障碍(ASD)人群发生物质使用障碍(SUD)风险较低的假设提出了质疑。总体而言,对于智力和发育障碍(/IDDs)人群中的 SUD 知之甚少。

目的

本研究旨在估计患有 ASD、ID 或 ASD+ID 的医疗补助受助人中 SUD 的患病率;描述这些人群和 SUD 类型;并确定群体内的人口统计学和临床特征与 SUD 风险的关系。

方法

我们使用 2008-2012 年全国医疗补助数据来识别患有 ASD、ID、ASD+ID 的受助人以及无 ASD/ID 的样本,并在这些个体中确定 SUD。我们使用描述性统计来描述受助人的群体和 SUD 类型,计算 SUD 的患病率,并使用修正泊松回归来检查残疾人群中 SUD 的调整后相对风险。

结果

SUD 的患病率在残疾人群中逐年增加,从 1-2.2%增加,在 ASD 人群中增加最快。在仅有 ID 的人群中,酒精滥用是最常见的 SUD(57%),而在仅有 ASD 的人群中,大麻滥用是最常见的 SUD(41%)。共患精神障碍(尤其是抑郁症)的人群 SUD 风险更高。

结论

结果突显了仅患有 ASD 和 ASD+ID 的医疗补助受助人中 SUD 的患病率不断增加,以及患有抑郁症和其他精神障碍的人群 SUD 风险更高。了解 I/DD 人群中 SUD 的筛查、诊断和治疗的机会,是未来研究的一个非常重要的问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dcd/9232987/523c7457b520/nihms-1788821-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dcd/9232987/523c7457b520/nihms-1788821-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3dcd/9232987/523c7457b520/nihms-1788821-f0001.jpg