• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

低成本电控气动复苏器的设计与分析,在 COVID-19 大流行期间为患者提供机械 AMBU 袋。

Design and Analysis of a Low-Cost Electronically Controlled Mobile Ventilator, Incorporating Mechanized AMBU Bag, for Patients during COVID-19 Pandemic.

机构信息

School of Nuclear Studies and Application, Jadavpur University, Kolkata 700032, India.

Department of Mechanical Engineering, Indian Institute of Technology, Madras, Tamil Nadu, India.

出版信息

J Healthc Eng. 2022 Mar 30;2022:6436818. doi: 10.1155/2022/6436818. eCollection 2022.

DOI:10.1155/2022/6436818
PMID:35368917
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8968386/
Abstract

The outbreak of novel COVID-19 has severely and unprecedentedly affected millions of people across the globe. The painful respiratory distress caused during this disease calls for external assistance to the victims in the form of ventilation. The most common types of artificial ventilating units available at the healthcare facilities and hospitals are exorbitantly expensive to manufacture, and their number is fairly inadequate even in the so-called developed countries to cater to the burning needs of an ever-increasing number of ailing human subjects. According to available reports, without the provision of ventilation, the novel COVID-19 patients are succumbing to their ailments in a huge number of cases. This colossal problem of the availability of ventilator units can be addressed to a great extent by readily producible and cost-effective ventilating units that can be used on those suffering patients during an acute emergency and in the absence of conventional expensive ventilators at hospitals and medical care units. This paper has made an attempt to design and simulate a simple, yet effective, mechanized ventilator unit, which can be conveniently assembled without a profuse skillset and operated to resuscitate an ailing human patient. The stepper motor-controlled kinematic linkage is designed to deliver the patient with a necessitated discharge of air at optimum oxygen saturation through the AMBU bag connected in a ventilation circuit. With the associated code on MATLAB, the motor control parameters such as angular displacement and speed are deduced according to the input patient conditions (age group, tidal volume, breathing rate, etc.) and thereafter fed to the controller that drives the stepper motor. With a proposed feedback loop, the real-time static and dynamic compliance, airway resistance values can be approximately determined from the pressure variation cycle and fed to the controller unit to adjust the tidal volume as and when necessary. The simplistic yet robust design not only renders easy manufacturability by conventional and rapid prototyping techniques like 3D printing at different scales but also makes the product easily portable with minimal handling difficulty. Keeping the motto of Health for All as envisioned by the WHO, this low-cost indigenously engineered ventilator will definitely help the poor and afflicted towards their right to health and will help the medical professionals buy some time to manage the patient with acute respiratory distress syndrome (ARDS) towards recovery. Moreover, this instrument mostly includes readily available functional units having standard specifications and can be considered as standard bought-out items.

摘要

新型 COVID-19 的爆发严重且前所未有地影响了全球数百万人。这种疾病导致的痛苦呼吸窘迫需要通过通气的方式为患者提供外部帮助。医疗机构和医院中最常见的人工通气设备制造起来非常昂贵,即使在所谓的发达国家,其数量也远远不足,难以满足越来越多患病患者的迫切需求。根据现有报告,如果不给新型 COVID-19 患者通气,大量患者将因疾病而死亡。在这种情况下,呼吸机数量不足的问题可以通过生产简易且经济高效的呼吸机在很大程度上得到解决,这些呼吸机可以在急性紧急情况下,在医院和医疗保健单位缺乏传统昂贵的呼吸机的情况下,用于治疗患病患者。本文试图设计和模拟一种简单而有效的机械化呼吸机单元,该单元可以方便地组装,而无需大量的技能,并可以在患者患病时进行操作以使其复苏。由步进电机控制的运动学连杆机构旨在通过连接在通气回路中的 AMBU 袋向患者输送必要的空气排放,以达到最佳的氧饱和度。通过与 MATLAB 相关联的代码,根据患者的输入条件(年龄组、潮气量、呼吸频率等)推导出电机控制参数,如角位移和速度,然后将其输入到驱动步进电机的控制器中。通过提出的反馈回路,可以根据压力变化周期大致确定实时静态和动态顺应性、气道阻力值,并将其反馈给控制器单元,以根据需要调整潮气量。这种简单而坚固的设计不仅可以通过传统的快速原型制造技术(如 3D 打印)在不同的规模上实现易于制造,而且还可以通过最小的处理难度使其产品易于携带。为了实现世界卫生组织所倡导的全民健康的宗旨,这种低成本的本土设计的呼吸机将肯定会帮助贫困和患病的人们实现他们的健康权利,并帮助医疗专业人员争取一些时间来管理患有急性呼吸窘迫综合征(ARDS)的患者,帮助他们恢复健康。此外,该仪器主要包括具有标准规格的现成功能单元,可以将其视为标准采购项目。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/30b37aaeb65b/JHE2022-6436818.012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/445f132bfc91/JHE2022-6436818.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/7c73982913b1/JHE2022-6436818.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/e77b1f450985/JHE2022-6436818.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/59a335a13b38/JHE2022-6436818.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/793bdf9a702a/JHE2022-6436818.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/8b6f76575481/JHE2022-6436818.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/33f40d96ebfa/JHE2022-6436818.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/7750344d73de/JHE2022-6436818.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/6357052d95ec/JHE2022-6436818.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/376ffedd82bd/JHE2022-6436818.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/30b37aaeb65b/JHE2022-6436818.012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/445f132bfc91/JHE2022-6436818.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/7c73982913b1/JHE2022-6436818.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/e77b1f450985/JHE2022-6436818.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/59a335a13b38/JHE2022-6436818.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/793bdf9a702a/JHE2022-6436818.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/8b6f76575481/JHE2022-6436818.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/33f40d96ebfa/JHE2022-6436818.007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/7750344d73de/JHE2022-6436818.008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/6357052d95ec/JHE2022-6436818.009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/376ffedd82bd/JHE2022-6436818.010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13d8/8968386/30b37aaeb65b/JHE2022-6436818.012.jpg

相似文献

1
Design and Analysis of a Low-Cost Electronically Controlled Mobile Ventilator, Incorporating Mechanized AMBU Bag, for Patients during COVID-19 Pandemic.低成本电控气动复苏器的设计与分析,在 COVID-19 大流行期间为患者提供机械 AMBU 袋。
J Healthc Eng. 2022 Mar 30;2022:6436818. doi: 10.1155/2022/6436818. eCollection 2022.
2
Increasing ventilator surge capacity in COVID 19 pandemic: design, manufacture and in vitro-in vivo testing in anaesthetized healthy pigs of a rapid prototyped mechanical ventilator.在新冠疫情期间提高呼吸机应急能力:一种快速成型机械呼吸机在麻醉健康猪身上的设计、制造及体外-体内测试
BMC Res Notes. 2020 Sep 7;13(1):421. doi: 10.1186/s13104-020-05259-z.
3
[Standard technical specifications for methacholine chloride (Methacholine) bronchial challenge test (2023)].[氯化乙酰甲胆碱支气管激发试验标准技术规范(2023年)]
Zhonghua Jie He He Hu Xi Za Zhi. 2024 Feb 12;47(2):101-119. doi: 10.3760/cma.j.cn112147-20231019-00247.
4
Shared Ventilation in the Era of COVID-19: A Theoretical Consideration of the Dangers and Potential Solutions.新冠疫情时代的共享通风:对危险和潜在解决方案的理论思考。
Respir Care. 2020 Jul;65(7):932-945. doi: 10.4187/respcare.07919. Epub 2020 May 6.
5
Computational simulation to assess patient safety of uncompensated COVID-19 two-patient ventilator sharing using the Pulse Physiology Engine.使用脉搏生理引擎评估 COVID-19 两患者呼吸机未补偿共享患者安全的计算模拟。
PLoS One. 2020 Nov 25;15(11):e0242532. doi: 10.1371/journal.pone.0242532. eCollection 2020.
6
Safety and Efficacy of Imatinib for Hospitalized Adults with COVID-19: A structured summary of a study protocol for a randomised controlled trial.COVID-19 住院成人患者使用伊马替尼的安全性和疗效:一项随机对照试验研究方案的结构化总结。
Trials. 2020 Oct 28;21(1):897. doi: 10.1186/s13063-020-04819-9.
7
[Effects of aerosol inhalation on respiratory mechanical parameters under different ventilation patterns and ventilator parameters].[不同通气模式及呼吸机参数下雾化吸入对呼吸力学参数的影响]
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Nov;30(11):1036-1040. doi: 10.3760/cma.j.issn.2095-4352.2018.011.005.
8
Do new anesthesia ventilators deliver small tidal volumes accurately during volume-controlled ventilation?新型麻醉呼吸机在容量控制通气期间能否准确输送小潮气量?
Anesth Analg. 2008 May;106(5):1392-400, table of contents. doi: 10.1213/ane.0b013e31816a68c6.
9
Intensive care for seriously ill patients affected by novel coronavirus sars - CoV - 2: Experience of the Crema Hospital, Italy.重症监护治疗新型冠状病毒 SARS-CoV-2 感染患者:意大利克雷马医院的经验。
Am J Emerg Med. 2021 Jul;45:156-161. doi: 10.1016/j.ajem.2020.08.005. Epub 2020 Aug 16.
10
[Clinical application of adaptive minute ventilation + IntelliCycle ventilation mode in patients with mild-to-moderate acute respiratory distress syndrome].适应性分钟通气量+智能循环通气模式在轻至中度急性呼吸窘迫综合征患者中的临床应用
Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2020 Jan;32(1):20-25. doi: 10.3760/cma.j.cn121430-20191012-00004.

引用本文的文献

1
COVID-19 Lessons Learned: Response to the Anticipated Ventilator Shortage.COVID-19 经验教训:应对预计的呼吸机短缺。
Respir Care. 2023 Jan;68(1):129-150. doi: 10.4187/respcare.10676.

本文引用的文献

1
Rapid Manufacturable Ventilator for Respiratory Emergencies of COVID-19 Disease.用于COVID-19疾病呼吸急救的快速可制造呼吸机
Trans Indian Natl Acad Eng. 2020;5(2):373-378. doi: 10.1007/s41403-020-00118-6. Epub 2020 Jun 7.
2
Preliminary Design and Development of a Mechanical Ventilator Using Industrial Automation Components for Rapid Deployment During the COVID-19 Pandemic.一种使用工业自动化组件的机械呼吸机的初步设计与开发,用于在新冠疫情期间快速部署
Cureus. 2021 Dec 13;13(12):e20386. doi: 10.7759/cureus.20386. eCollection 2021 Dec.
3
Design and analysis of a mechanical ventilation system based on cams.
基于凸轮的机械通风系统的设计与分析
Heliyon. 2021 Oct;7(10):e08195. doi: 10.1016/j.heliyon.2021.e08195. Epub 2021 Oct 19.
4
Association between lung compliance phenotypes and mortality in COVID-19 patients with acute respiratory distress syndrome.新型冠状病毒肺炎急性呼吸窘迫综合征患者肺顺应性表型与死亡率的关系
Ann Acad Med Singap. 2021 Sep;50(9):686-694. doi: 10.47102/annals-acadmedsg.2021129.
5
Design and simulation of mechanical ventilators.机械通气机的设计与仿真
Chaos Solitons Fractals. 2021 Sep;150:111169. doi: 10.1016/j.chaos.2021.111169. Epub 2021 Jun 25.
6
GlasVent-The Rapidly Deployable Emergency Ventilator.格拉斯文特——快速部署应急呼吸机。
Glob Chall. 2020 Sep 6;4(12):2000046. doi: 10.1002/gch2.202000046. eCollection 2020 Dec.
7
A Novel Low-Cost Ventilator for Use in a Worldwide Pandemic: The Portsmouth Ventilator.一种用于全球大流行的新型低成本呼吸机:朴茨茅斯呼吸机。
Crit Care Explor. 2020 Dec 2;2(12):e0292. doi: 10.1097/CCE.0000000000000292. eCollection 2020 Dec.
8
Pulmonary pathology of ARDS in COVID-19: A pathological review for clinicians.新型冠状病毒肺炎急性呼吸窘迫综合征的肺部病理学:临床医生的病理评估。
Respir Med. 2021 Jan;176:106239. doi: 10.1016/j.rmed.2020.106239. Epub 2020 Nov 19.
9
AmbuBox: A Fast-Deployable Low-Cost Ventilator for COVID-19 Emergent Care.AmbuBox:一种用于 COVID-19 紧急护理的快速部署、低成本呼吸机。
SLAS Technol. 2020 Dec;25(6):573-584. doi: 10.1177/2472630320953801. Epub 2020 Sep 3.
10
MADVent: A low-cost ventilator for patients with COVID-19.MADVent:一种用于新冠肺炎患者的低成本呼吸机。
Med Devices Sens. 2020 Aug;3(4):e10106. doi: 10.1002/mds3.10106. Epub 2020 Jun 27.