• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

2001 年至 2019 年英国肺癌的流行病学研究与临床用药。

Epidemiological Study of Lung Cancer and Clinical Medication in England from 2001 to 2019.

机构信息

The University of Sheffield, Western Bank, Sheffield S10 2TN, UK.

出版信息

J Healthc Eng. 2022 Mar 23;2022:3577312. doi: 10.1155/2022/3577312. eCollection 2022.

DOI:10.1155/2022/3577312
PMID:35368924
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8967509/
Abstract

We aimed to explore the epidemiological characteristics and changes of lung cancer and the clinical medication in England from 2001 to 2019. We searched related research using search engine systems such as MEDLINE, PubMed, and PsychINFO. Lung cancer is a serious disease and the prognosis is usually very poor. The overall mortality rate of lung cancer decreased year by year in England from 2001 to 2019, but men, the elderly, and people exposed to polluted air are still more likely to be infected with lung cancer or die as a result, the prevalence and mortality rate of lung cancer in the north of England is significantly higher than that in the south, and the gap is increasing year by year. Lung cancer has changeable risk factors such as quitting smoking and improving air quality, which can effectively reduce the related risk. Paclitaxel, docetaxel, gemcitabine, and vinorelbine are the main drugs for the treatment of lung cancer in England and the treatment of these drugs is beneficial to the survival and quality of life of patients. Men and the elderly are at high risk of lung cancer, which means that lung cancer has obvious gender inequality and age inequality. At the same time, based on the statistical data of lung cancer risk in different regions, it can be concluded that lung cancer also has strong geographical and economic inequality. Changing risk factors and using drugs can effectively reduce the risk of lung cancer and provide effective treatment.

摘要

我们旨在探索 2001 年至 2019 年期间英国肺癌的流行病学特征和变化,以及临床用药情况。我们使用 MEDLINE、PubMed 和 PsychINFO 等搜索引擎系统搜索了相关研究。

肺癌是一种严重的疾病,预后通常很差。从 2001 年到 2019 年,英国肺癌的总体死亡率逐年下降,但男性、老年人和暴露于污染空气中的人仍然更容易感染肺癌或因此死亡,英格兰北部的肺癌发病率和死亡率明显高于南部,且差距逐年增大。肺癌的风险因素如戒烟和改善空气质量等变化多样,这些因素可以有效地降低相关风险。紫杉醇、多西他赛、吉西他滨和长春瑞滨是英国治疗肺癌的主要药物,这些药物的治疗对患者的生存和生活质量有益。

男性和老年人患肺癌的风险较高,这意味着肺癌存在明显的性别不平等和年龄不平等。同时,基于不同地区肺癌风险的统计数据,可以得出结论,肺癌还存在强烈的地理和经济不平等。改变风险因素和使用药物可以有效地降低肺癌风险,并提供有效的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/714a/8967509/2d3ea7672bee/JHE2022-3577312.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/714a/8967509/50a45011adf0/JHE2022-3577312.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/714a/8967509/5dbfc324d749/JHE2022-3577312.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/714a/8967509/0a1de2035ec0/JHE2022-3577312.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/714a/8967509/2d3ea7672bee/JHE2022-3577312.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/714a/8967509/50a45011adf0/JHE2022-3577312.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/714a/8967509/5dbfc324d749/JHE2022-3577312.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/714a/8967509/0a1de2035ec0/JHE2022-3577312.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/714a/8967509/2d3ea7672bee/JHE2022-3577312.004.jpg

相似文献

1
Epidemiological Study of Lung Cancer and Clinical Medication in England from 2001 to 2019.2001 年至 2019 年英国肺癌的流行病学研究与临床用药。
J Healthc Eng. 2022 Mar 23;2022:3577312. doi: 10.1155/2022/3577312. eCollection 2022.
2
A rapid and systematic review of the clinical effectiveness and cost-effectiveness of paclitaxel, docetaxel, gemcitabine and vinorelbine in non-small-cell lung cancer.对紫杉醇、多西他赛、吉西他滨和长春瑞滨在非小细胞肺癌中的临床疗效和成本效益进行的快速系统评价。
Health Technol Assess. 2001;5(32):1-195. doi: 10.3310/hta5320.
3
Clinical and cost effectiveness of paclitaxel, docetaxel, gemcitabine, and vinorelbine in non-small cell lung cancer: a systematic review.紫杉醇、多西他赛、吉西他滨和长春瑞滨治疗非小细胞肺癌的临床疗效及成本效益:一项系统评价
Thorax. 2002 Jan;57(1):20-8. doi: 10.1136/thorax.57.1.20.
4
Meeting the chemotherapy needs of elderly and poor performance status patients with NSCLC.满足老年及身体状况较差的非小细胞肺癌患者的化疗需求。
Lung Cancer. 2002 Dec;38 Suppl 4:37-41. doi: 10.1016/s0169-5002(02)00170-8.
5
Does chemotherapy have a role as palliative therapy for unfit or elderly patients with non-small-cell lung cancer?对于身体状况不佳或老年非小细胞肺癌患者,化疗作为姑息治疗手段是否有作用?
Lung Cancer. 2002 Nov;38 Suppl 2:S45-50. doi: 10.1016/s0169-5002(02)00357-4.
6
A randomized phase II trial of single-agent gemcitabine, vinorelbine, or docetaxel in patients with advanced non-small cell lung cancer who have poor performance status and/or are elderly.一项针对体能状态较差和/或年龄较大的晚期非小细胞肺癌患者,使用吉西他滨、长春瑞滨或多西他赛单药治疗的随机II期试验。
J Thorac Oncol. 2007 Mar;2(3):230-6. doi: 10.1097/JTO.0b013e318031d06f.
7
Vinorelbine plus gemcitabine followed by docetaxel versus carboplatin plus paclitaxel in patients with advanced non-small-cell lung cancer: a randomised, open-label, phase III study.长春瑞滨联合吉西他滨序贯多西他赛与卡铂联合紫杉醇治疗晚期非小细胞肺癌患者的随机、开放标签、III期研究
Lancet Oncol. 2008 Dec;9(12):1135-42. doi: 10.1016/S1470-2045(08)70261-4. Epub 2008 Nov 13.
8
A meta-analysis of platinum plus gemcitabine or vinorelbine in the treatment of advanced non-small-cell lung cancer.铂类联合吉西他滨或长春瑞滨治疗晚期非小细胞肺癌的荟萃分析
Lung Cancer. 2009 Sep;65(3):339-44. doi: 10.1016/j.lungcan.2008.11.019. Epub 2009 Jan 13.
9
Chemotherapy for elderly patients with advanced non-small-cell lung cancer: the Multicenter Italian Lung Cancer in the Elderly Study (MILES) phase III randomized trial.老年晚期非小细胞肺癌患者的化疗:意大利老年肺癌多中心研究(MILES)III期随机试验
J Natl Cancer Inst. 2003 Mar 5;95(5):362-72. doi: 10.1093/jnci/95.5.362.
10
Weekly docetaxel with either gemcitabine or vinorelbine as second-line treatment in patients with advanced nonsmall cell lung carcinoma: Phase II trials of the Minnie Pearl Cancer Research Network.多西他赛联合吉西他滨或长春瑞滨作为晚期非小细胞肺癌患者二线治疗的每周方案:米妮·珀尔癌症研究网络的II期试验
Cancer. 2001 Nov 1;92(9):2391-8. doi: 10.1002/1097-0142(20011101)92:9<2391::aid-cncr1587>3.0.co;2-m.

引用本文的文献

1
Changing trends in lung cancer disease burden between China and Australia from 1990 to 2019 and its predictions.1990年至2019年中国与澳大利亚肺癌疾病负担的变化趋势及其预测。
Thorac Cancer. 2025 Jan;16(2):e15430. doi: 10.1111/1759-7714.15430. Epub 2024 Dec 12.
2
Chronic Pulmonary Aspergillosis after Surgical Treatment for Non-Small Cell Lung Cancer-An Analysis of Risk Factors and Clinical Outcomes.非小细胞肺癌手术治疗后慢性肺曲霉病——危险因素及临床结局分析
J Fungi (Basel). 2024 May 6;10(5):335. doi: 10.3390/jof10050335.
3
Retracted: Epidemiological Study of Lung Cancer and Clinical Medication in England from 2001 to 2019.

本文引用的文献

1
The relationship between chronic lung diseases and lung cancer - a narrative review.慢性肺部疾病与肺癌的关系——一篇叙述性综述。
J BUON. 2020 Jul-Aug;25(4):1687-1692.
2
Cancer morbidity trends and regional differences in England-A Bayesian analysis.英格兰癌症发病率趋势和区域差异——贝叶斯分析。
PLoS One. 2020 May 20;15(5):e0232844. doi: 10.1371/journal.pone.0232844. eCollection 2020.
3
Epidemiology of lung cancer in China.中国肺癌的流行病学。
撤回:2001年至2019年英国肺癌与临床用药的流行病学研究。
J Healthc Eng. 2023 Oct 4;2023:9894620. doi: 10.1155/2023/9894620. eCollection 2023.
Thorac Cancer. 2019 Jan;10(1):3-7. doi: 10.1111/1759-7714.12916. Epub 2018 Nov 28.
4
Serum 25(OH)D concentration, common variants of the VDR gene and lung cancer occurrence.血清 25(OH)D 浓度、VDR 基因常见变异与肺癌发生。
Int J Cancer. 2017 Jul 15;141(2):336-341. doi: 10.1002/ijc.30740. Epub 2017 Apr 24.
5
Confidence intervals for directly standardized rates using mid-p gamma intervals.使用中间p伽马区间的直接标准化率的置信区间。
Biom J. 2017 Mar;59(2):377-387. doi: 10.1002/bimj.201600111. Epub 2016 Dec 23.
6
COPD, emphysema and the onset of lung cancer. A systematic review.COPD、肺气肿与肺癌发病。系统综述。
Cancer Lett. 2016 Nov 28;382(2):240-244. doi: 10.1016/j.canlet.2016.09.002. Epub 2016 Sep 22.
7
Occupational asbestos exposure and lung cancer--a systematic review of the literature.职业性石棉暴露与肺癌——文献系统综述
Arch Environ Occup Health. 2014;69(4):191-206. doi: 10.1080/19338244.2013.863752.
8
The 21st century hazards of smoking and benefits of stopping: a prospective study of one million women in the UK.21 世纪吸烟的危害与戒烟的益处:英国一项对 100 万名女性的前瞻性研究。
Lancet. 2013 Jan 12;381(9861):133-41. doi: 10.1016/S0140-6736(12)61720-6. Epub 2012 Oct 27.
9
Diagnosis and treatment of lung cancer: summary of updated NICE guidance.肺癌的诊断与治疗:英国国家卫生与临床优化研究所(NICE)最新指南总结
BMJ. 2011 Apr 27;342:d2110. doi: 10.1136/bmj.d2110.
10
Tobacco smoking and cancer: a brief review of recent epidemiological evidence.吸烟与癌症:近期流行病学证据简述
Lung Cancer. 2004 Aug;45 Suppl 2:S3-9. doi: 10.1016/j.lungcan.2004.07.998.