在儿科人群中使用系统性阿维A的利弊。
Pros and cons of using systemic acitretin in the paediatric population.
作者信息
Sadowska Magdalena, Narbutt Joanna, Skibińska Małgorzata, Lesiak Aleksandra
机构信息
Department of Dermatology, Paediatric Dermatology and Oncology, Medical University of Lodz, Lodz, Poland.
出版信息
Postepy Dermatol Alergol. 2022 Feb;39(1):34-38. doi: 10.5114/ada.2020.98558. Epub 2020 Sep 1.
Abstract
Acitretin, a synthetic analogue of vitamin A is widely used in dermatology. It has an important role in the treatment of psoriasis and keratinization disorders. In adults its safety and efficacy has been proven in many studies, but there are some concerns regarding the use of acitretin in paediatric population, especially in high doses and as a long-term therapy. In this article we present the main indications of acitretin in children as well as the positive and negative aspects of acitretin treatment in this age population.
摘要
阿维A，一种维生素A的合成类似物，在皮肤科广泛应用。它在银屑病和角化异常疾病的治疗中发挥着重要作用。在成人中，其安全性和有效性已在多项研究中得到证实，但对于阿维A在儿科人群中的使用，尤其是高剂量和长期治疗，仍存在一些担忧。在本文中，我们介绍了阿维A在儿童中的主要适应证，以及该年龄段阿维A治疗的利弊。
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