阿维 A 在皮肤科的应用。
Acitretin Use in Dermatology.
机构信息
1 Guenther Research Inc., London, ON, Canada.
2 Western University, London, ON, Canada.
出版信息
J Cutan Med Surg. 2017 Nov/Dec;21(3_suppl):2S-12S. doi: 10.1177/1203475417733414. Epub 2017 Sep 27.
BACKGROUND
Acitretin has been used for the treatment of severe psoriasis for over 20 years.
OBJECTIVE
The current project was conceived to optimise patient care by recognising the role acitretin can play in the treatment of patients with psoriasis and those with other disorders of keratinisation.
METHODS
A literature review was conducted to explore the role of acitretin and to assess its value for dermatologic disorders other than severe psoriasis. A panel of Canadian dermatologists developed a clinical pathway using a case-based approach, focusing on specific patient features.
RESULTS
The clinical pathway covers plaque psoriasis with hyperkeratotic plantar disease, palmoplantar pustulosis, hyperkeratotic hand dermatitis, lichen planus, lamellar ichthyosis, and hidradenitis suppurativa.
CONCLUSION
The recommendations in our clinical pathway reflect the current use of acitretin in Canada for severe psoriasis and other disorders of keratinisation.
背景
阿维 A 酯已被用于治疗严重银屑病超过 20 年。
目的
本项目旨在通过认识到阿维 A 酯在治疗银屑病患者和其他角化障碍患者中的作用，优化患者护理。
方法
进行了文献回顾，以探讨阿维 A 酯的作用，并评估其在除严重银屑病以外的皮肤科疾病中的价值。一组加拿大皮肤科医生使用基于病例的方法制定了临床路径，重点关注特定的患者特征。
结果
临床路径涵盖了伴有过度角化性足底病的斑块状银屑病、掌跖脓疱病、过度角化性手部皮炎、扁平苔藓、板层状鱼鳞癣和化脓性汗腺炎。
结论
我们临床路径中的建议反映了阿维 A 酯在加拿大治疗严重银屑病和其他角化障碍的当前应用。
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