Arslan Başak, Yıldırım Ertan, Bodur Onur Can, Baloş Tuncer Burcu, Ulusoy Mehmet Çağrı, Tuncer Cumhur
Department of Orthodontics, Gazi University Faculty of Dentistry, Ankara, Turkey.
Department of Chemistry, Gazi University Faculty of Science, Ankara, Turkey.
Turk J Orthod. 2022 Mar;35(1):27-32. doi: 10.5152/TurkJOrthod.2021.21176.
To assess the levels of bisphenol A (BPA) released from an orthodontic adhesive with respect to the effects of tooth brushing and mouth washing.
Three groups, each containing fifteen adhesive samples were prepared. In Group 1, samples were polymerized according to manufacturer instructions. In Group 2, after the same polymerization protocol, each sample was brushed with a fluoride-containing toothpaste. For Group 3, samples were immersed in a mouth washing solution after polymerization. Later, all samples were placed into glass tubes containing 5 mL distilled water. High-performance liquid chromatography (HPLC) measurements were performed to assess the leaching amount of BPA. Intergroup comparison was performed by one way ANOVA test.
Mean amounts of BPA were found to be 0.2674 µg/L, 0.2692 µg/L, and 0.2705 µg/L, respectively. Only a significant difference was found between Group 1 and 3 (P < .01), revealing higher BPA levels with the mouth washing solution.
Measurable amounts of BPA release were observed in all groups of orthodontic adhesive samples, but the detected amounts were below the toxic levels. From a clinical point of view, alcohol-containing mouth washing solutions might increase the amount of leaching monomer, since alcohol is solvent of BPA.
评估正畸粘合剂释放的双酚A（BPA）水平与刷牙和漱口效果的关系。
制备三组，每组包含15个粘合剂样本。第1组，样本按照制造商说明进行聚合。第2组，在相同的聚合方案后，每个样本用含氟牙膏刷牙。对于第3组，样本在聚合后浸入漱口液中。之后，将所有样本放入含有5 mL蒸馏水的玻璃管中。采用高效液相色谱（HPLC）测量来评估BPA的浸出量。通过单因素方差分析进行组间比较。
发现BPA的平均含量分别为0.2674 µg/L、0.2692 µg/L和0.2705 µg/L。仅在第1组和第3组之间发现显著差异（P <.01），表明漱口液中的BPA水平更高。
在所有组的正畸粘合剂样本中均观察到可测量的BPA释放量，但检测到的量低于有毒水平。从临床角度来看，含酒精的漱口液可能会增加浸出单体的量，因为酒精是BPA的溶剂。
