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双表达阑尾伯基特淋巴瘤:一例报告及文献综述

Double-Expressor Appendiceal Burkitt's Lymphoma: A Case Report and Literature Review.

作者信息

Dukmak Osama N, Abugharbieh Hamzeh M I, Emar Mohammad Farid, Khamayseh Iman, M Tos Salem, Salhab Rafiq

机构信息

Al-Quds University, Faculty of Medicine, Jerusalem, State of Palestine.

Al-Ahli Hospital, Hebron, State of Palestine.

出版信息

Case Rep Hematol. 2022 Mar 25;2022:6795699. doi: 10.1155/2022/6795699. eCollection 2022.

Abstract

BACKGROUND

Appendiceal lymphoma is a very rare entity accounting for 0.015% of all gastrointestinal lymphoma cases. Acute appendicitis is the most common presentation of primary appendix neoplasms. Burkitt's lymphoma presenting as an acute appendicitis is a rare entity with around 21% of the cases presenting as a lower iliac fossa mass. . A 23-year-old male was admitted to the surgical ward as a case of acute appendicitis with localized tenderness in the right iliac fossa, positive rebound tenderness, a positive Rovsing's sign, and ultrasound findings of suspected complicated appendicitis. Appendectomy was performed. Histopathological examination of the appendectomy specimen revealed a double-expressor non-Hodgkin diffuse large cell lymphoma with Burkitt's-like morphology. He was sent for chemotherapy treatment.

CONCLUSION

Only 34 cases of Burkitt's lymphoma have been reported to present as acute appendicitis. Histological examination following appendectomy for an apparent appendicitis is essential. Furthermore, complete blood count and a computed tomography scan aid the diagnosis of lymphoma. Double-expressor lymphoma has been shown to have poor outcomes. Therefore, prompt and aggressive treatment is vital.

摘要

背景

阑尾淋巴瘤是一种非常罕见的疾病,占所有胃肠道淋巴瘤病例的0.015%。急性阑尾炎是原发性阑尾肿瘤最常见的表现形式。以急性阑尾炎形式出现的伯基特淋巴瘤是一种罕见的疾病,约21%的病例表现为右下腹包块。一名23岁男性因急性阑尾炎入院,右下腹有局限性压痛、反跳痛阳性、罗夫辛氏征阳性,超声检查结果提示疑似复杂性阑尾炎。遂行阑尾切除术。阑尾切除标本的组织病理学检查显示为具有伯基特样形态的双表达非霍奇金弥漫大细胞淋巴瘤。他被送去接受化疗。

结论

据报道,仅34例伯基特淋巴瘤表现为急性阑尾炎。对疑似阑尾炎行阑尾切除术后进行组织学检查至关重要。此外,全血细胞计数和计算机断层扫描有助于淋巴瘤的诊断。双表达淋巴瘤已被证明预后较差。因此,及时且积极的治疗至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/371d/8975681/c2cd86fbe48a/CRIHEM2022-6795699.001.jpg

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