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潜在活体肾脏供者的风险评估和管理:“第三方”委员会的作用。

Risk Assessment and Management for Potential Living Kidney Donors: The Role of "Third-Party" Commission.

机构信息

Section of Legal Medicine, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy.

Clinical Risk Management Unit, University Hospital Città della Salute e della Scienza di Torino, Turin, Italy.

出版信息

Front Public Health. 2022 Mar 17;10:824048. doi: 10.3389/fpubh.2022.824048. eCollection 2022.

DOI:10.3389/fpubh.2022.824048
PMID:35372186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8968079/
Abstract

Living kidney donation is the most common type of living-donor transplant. Italian guidelines allow the living donations from emotionally related donors only after clear and voluntary consent expressed by both the donor and the recipient involved. Living donation raises ethical and legal issues because donors voluntarily undergo a surgical procedure to remove a healthy kidney in order to help another person. According to the Italian standards, the assessment of living donor-recipient pair has to be conducted by a medical "third party", completely independent from both the patients involved and the medical team treating the recipient. Starting from the Hospital "Città della Salute e della Scienza" of Turin (Italy) experience, including 116 living kidney donations, the Authors divided the evaluation process performed by the "Third-Party" Commission into four stages, with a particular attention to the potential donor. Living donation procedures should reflect fiduciary duties that healthcare providers have toward their patients, originating from the relationship of trust between physician and patient. In addition to that, the social implications are enormous if one considers the worldwide campaigns to promote public awareness about organ donation and transplantation, and to encourage people to register their organ donation decisions. The systematic process proposed here can be a tool that proactively reduces and controls the risks of coercion, organ trafficking, vitiated consent, insufficient weighting of donative choice, that could arise especially in donors involved in living kidney donation.

摘要

活体肾捐赠是最常见的活体供肾移植类型。意大利的指导方针仅允许在有情感关系的供者在供者和受者双方明确和自愿表示同意的情况下进行活体捐赠。活体捐赠引发了伦理和法律问题,因为供者自愿接受手术以切除健康的肾脏来帮助他人。根据意大利的标准,对活体供受者配对的评估必须由医疗“第三方”进行,该第三方完全独立于涉及的患者和治疗受者的医疗团队。从意大利都灵的“Città della Salute e della Scienza”医院的经验开始,包括 116 例活体肾脏捐赠,作者将“第三方”委员会进行的评估过程分为四个阶段,特别关注潜在供者。活体捐赠程序应反映医疗保健提供者对其患者的信托责任,这种责任源于医生和患者之间的信任关系。此外,如果考虑到全球范围内宣传器官捐赠和移植的公众意识,并鼓励人们登记他们的器官捐赠决定的宣传活动,那么社会影响是巨大的。这里提出的系统过程可以是一种工具,可以主动减少和控制胁迫、器官贩卖、同意被篡改、捐赠选择权重不足等风险,这些风险尤其可能出现在参与活体肾脏捐赠的供者中。

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本文引用的文献

1
Psychiatric and psychological evaluation in living donor kidney transplantation: a single center experience.活体供肾移植中的精神和心理评估:单中心经验。
G Ital Nefrol. 2021 Feb 16;38(1):2021-vol1.
2
Psychosocial risk factors for impaired health-related quality of life in living kidney donors: results from the ELIPSY prospective study.生活肾捐献者健康相关生活质量受损的社会心理风险因素:ELIPSY 前瞻性研究结果。
Sci Rep. 2020 Dec 7;10(1):21343. doi: 10.1038/s41598-020-78032-8.
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Extended Criteria Donors in Living Kidney Transplantation Including Donor Age, Smoking, Hypertension and BMI.活体肾移植中的扩大标准供体,包括供体年龄、吸烟、高血压和体重指数。
Ther Clin Risk Manag. 2020 Aug 24;16:787-793. doi: 10.2147/TCRM.S256962. eCollection 2020.
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COVID-19 and kidney transplantation: an Italian Survey and Consensus.COVID-19 与肾移植:意大利调查与共识。
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New Rules on Patient's Safety and Professional Liability for the Italian Health Service.意大利卫生服务患者安全和专业责任新规则。
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Partnership Satisfaction in Living Kidney Donors.
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Guidelines and best practices: remarks on the Gelli-Bianco law.指南与最佳实践:关于《杰利-比安科法》的评论
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The donor advocacy team: a risk management program for living organ, tissue, and cell transplant donors.供体宣传团队:一项针对活体器官、组织和细胞移植供体的风险管理计划。
Surg Today. 2017 Aug;47(8):980-985. doi: 10.1007/s00595-017-1468-z. Epub 2017 Feb 15.