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活体供肾移植中的精神和心理评估:单中心经验。

Psychiatric and psychological evaluation in living donor kidney transplantation: a single center experience.

机构信息

Dipartimento di scienze del Sistema nervoso e del comportamento, Università di Pavia, Italia.

UOC Nefrologia, Dialisi, Trapianto, Fondazione IRCCS Policlinico San Matteo, Pavia, Italia.

出版信息

G Ital Nefrol. 2021 Feb 16;38(1):2021-vol1.

Abstract

Living donor kidney transplantation (LDKT) is the treatment of choice for end stage renal disease. LDKT involves complex psychosocial issues, which remain partially unexplored. The study involved all potential living donors and recipient pairs consecutively referred for psychosocial evaluation from the nephrologist. Clinical and sociodemographic variables including prior psychiatric history, previous and current use of psychopharmacological therapy, motivation and information about the transplant procedure were collected. Study participants completed the Symptom Checklist-90-R (SCL-90-R) to assess psychopathological distress. Fifty-three donor/recipient pairs underwent psychiatric and psychological evaluation. Seven subjects (13%) in the recipient group and 13 subjects (25%) in the donor group reported a history of psychological distress and/or psychiatric conditions. A psychiatric diagnosis was confirmed in 4 recipients (7.5% of the study sample, including autism spectrum disorder, histrionic personality disorder, and anxiety-depressive disorders) and 5 donors (9%, including narcissistic personality disorder in one case and anxiety-depressive disorders). SCL-90-R GSI mean scores were 0.3 ±0.3 and 0.2 ±0.2 for the recipient and donor groups, respectively. Overall, 8 couples (15%) suspended the living donation pathway before transplantation. Four couples were excluded for a new onset medical condition. The psychological and psychiatric evaluation excluded one candidate. One couple dropped out before completing the scheduled exams. One recipient refused to undergo crossover renal transplantation, while 1 donor candidate withdrew her consent for transplantation at the end of the evaluation process. Limited but significant psychopathological distress in donors and recipients supports the usefulness of psychiatric and psychological competencies within the transplant team.

摘要

活体供肾移植(LDKT)是治疗终末期肾病的首选方法。LDKT 涉及复杂的社会心理问题,这些问题仍在部分探索中。该研究涉及所有潜在的活体供者和受者对,他们是连续从肾病学家处转介来进行社会心理评估的。收集了临床和社会人口统计学变量,包括既往精神病史、既往和当前使用精神药理学治疗、动机以及关于移植程序的信息。研究参与者完成了症状清单 90-R(SCL-90-R),以评估心理病理困扰。53 对供者/受者对接受了精神病学和心理学评估。受者组中有 7 名(13%)和供者组中有 13 名(25%)受试者报告有心理困扰和/或精神疾病史。在 4 名受者(研究样本的 7.5%,包括自闭症谱系障碍、戏剧型人格障碍和焦虑抑郁障碍)和 5 名供者(9%,包括自恋型人格障碍和焦虑抑郁障碍)中确诊为精神疾病。SCL-90-R GSI 平均得分分别为 0.3 ±0.3 和 0.2 ±0.2,供者组和受者组。总体而言,8 对夫妇(15%)在移植前暂停了活体供肾途径。4 对夫妇因新出现的医疗状况而被排除。心理和精神病学评估排除了一名候选人。一对夫妇在完成预定检查前退出。一名受者拒绝接受交叉肾移植,而 1 名供者候选人在评估过程结束时撤回了她的移植同意。供者和受者有限但明显的心理病理困扰支持在移植团队中使用精神病学和心理学能力。

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