Nonpassopon Manachai, Jongkhajornpong Passara, Phimpho Prae, Cheewaruangroj Nontawat, Lekhanont Kaevalin, Chuckpaiwong Varintorn
Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
BMJ Open Ophthalmol. 2022 Mar 8;7(1):e000941. doi: 10.1136/bmjophth-2021-000941. eCollection 2022.
To assess agreement and repeatability of white-to-white (WTW) and anterior chamber depth (ACD), and agreement of implantable collamer lens (ICL) size using these measurements from different devices.
A retrospective review of 83 eyes with ICL implantation (42 patients) was conducted. The agreement of WTW (measured with WaveLight Topolyzer and Orbscan IIz) and ACD (measured with WaveLight Oculyzer and Orbscan IIz) was analysed. Correlation of ICL sizes and difference of eyes with unacceptable vaults between two data sets (WaveLight platform; Topolyzer and Oculyzer and Orbscan IIz) were assessed.
Average WTW measured by Orbscan IIz and Topolyzer demonstrated good agreement (Ρ 0.884) with low systematic bias (-0.03±0.1 mm) and narrow 95% limits of agreement (LoA) of -0.28 to 0.22. Average ACD measured by Orbscan IIz and Oculyzer also showed good agreement (Ρ 0.903) with low systematic bias (-0.04±0.1 mm) and relatively narrow 95% LoA (0.2 to 0.12). ICL size selected according to two data sets showed moderate to strong level of agreement (Kappa=0.81). There was a statistically significant difference (p<0.001) in the proportion of eyes with unacceptable postoperative vaults when using the Wavelight platform data set (five eyes, 6.02%) and the Orbscan IIz data set (12 eyes, 14.46%).
Although the agreement of WTW and ACD between devices was good, there was a significant difference in proportion of eyes with unacceptable postoperative vaults when using two data sets. Therefore, Topolyzer and Oculyzer might not be suitable for operating interchangeably with Orbscan IIz for ICL size selection.
评估白对白（WTW）和前房深度（ACD）测量值的一致性和可重复性，以及使用不同设备的这些测量值来确定可植入式角膜接触镜（ICL）尺寸的一致性。
对83只接受ICL植入术的眼睛（42例患者）进行回顾性研究。分析WTW（用WaveLight Topolyzer和Orbscan IIz测量）和ACD（用WaveLight Oculyzer和Orbscan IIz测量）的一致性。评估两个数据集（WaveLight平台；Topolyzer和Oculyzer以及Orbscan IIz）之间ICL尺寸的相关性以及术后房拱不良的眼睛的差异。
Orbscan IIz和Topolyzer测量的平均WTW显示出良好的一致性（Ρ 0.884），系统偏差较低（-0.03±0.1毫米），95%一致性界限（LoA）较窄，为-0.28至0.22。Orbscan IIz和Oculyzer测量的平均ACD也显示出良好的一致性（Ρ 0.903），系统偏差较低（-0.04±0.1毫米），95% LoA相对较窄（0.2至0.12）。根据两个数据集选择的ICL尺寸显示出中度至高度的一致性（Kappa = 0.81）。使用WaveLight平台数据集（5只眼，6.02%）和Orbscan IIz数据集（12只眼，14.46%）时，术后房拱不良的眼睛比例存在统计学显著差异（p < 0.001）。
虽然不同设备之间WTW和ACD的一致性良好，但使用两个数据集时，术后房拱不良的眼睛比例存在显著差异。因此，Topolyzer和Oculyzer可能不适用于与Orbscan IIz互换操作以选择ICL尺寸。
