School of Nursing & Health Studies, University of Miami, Coral Gables, USA.
School of Nursing & Health Studies, University of Miami, Coral Gables, USA.
Eur J Oncol Nurs. 2022 Jun;58:102136. doi: 10.1016/j.ejon.2022.102136. Epub 2022 Mar 28.
Colorectal cancer (CRC) survivors are living longer; therefore, factors that improve outcomes, like symptom management and quality of life (QoL), have increasingly become important. This study examined CRC survivors' symptom(s) characteristics, positive psychology (benefit finding and post-traumatic growth), and QoL, and determined whether positive psychology mediates symptom(s) and QoL relationship during acute cancer survivorship.
A cross-sectional study of 117 CRC survivors was conducted at a National Cancer Institute-Designated Cancer Center. Data were collected by demographic questionnaire, Therapy-Related Symptom Checklist, QoL Inventory, and positive psychology assessed by Carver Benefit-Finding Scale and Post-Traumatic Growth Inventory. Descriptive statistics, between-group differences, multiple linear regression, and mediation analyses were performed.
Top common symptoms were peripheral neuropathy, fatigue/feeling sluggish, skin changes, sleep disturbances, and weakness. Psychological distress symptoms were reported in 38.46% of CRC survivors, and moderate-to-high positive psychology (3.21 ± 1.09) and QoL (5.15 ±0 .52) levels were reported during acute cancer survivorship. Significant (p < 0.05) relationships were observed between QoL and (a) number of symptoms, (b) psychological distress symptoms, (c) benefit finding, (d) post-traumatic growth, and (e) positive psychology. Positive psychology partially mediated the relationship between symptom frequency and QoL (p < 0.05).
Our study's findings suggest that CRC survivors positively cope with their cancer and treatment, and positive psychology partially mediates the relationship between symptoms frequency (almost daily and daily vs. random) and QoL across acute cancer survivorship. Identifying how CRC survivors adjust to their cancer may help healthcare teams provide tailored self-management skills to promote QoL and reduce symptom burden throughout cancer survivorship.
结直肠癌（CRC）幸存者的寿命越来越长；因此，改善预后的因素，如症状管理和生活质量（QoL），变得越来越重要。本研究调查了 CRC 幸存者的症状特征、积极心理学（获益发现和创伤后成长）和 QoL，并确定积极心理学是否在急性癌症生存期间调节症状和 QoL 之间的关系。
在一家美国国立癌症研究所指定的癌症中心进行了一项 117 名 CRC 幸存者的横断面研究。通过人口统计学问卷、治疗相关症状清单、QoL 量表和积极心理学（由获益发现量表和创伤后成长量表评估）收集数据。进行描述性统计、组间差异、多元线性回归和中介分析。
最常见的症状是周围神经病变、疲劳/感觉迟钝、皮肤变化、睡眠障碍和虚弱。38.46%的 CRC 幸存者报告有心理困扰症状，在急性癌症生存期间报告有中度至高度积极的心理学（3.21±1.09）和 QoL（5.15±0.52）水平。在 QoL 与（a）症状数量、（b）心理困扰症状、（c）获益发现、（d）创伤后成长和（e）积极心理学之间观察到显著（p<0.05）的关系。积极心理学部分中介了症状频率与 QoL 之间的关系（p<0.05）。
我们的研究结果表明，CRC 幸存者积极应对癌症和治疗，积极心理学部分中介了症状频率（几乎每天和每天与随机）与急性癌症生存期间 QoL 之间的关系。确定 CRC 幸存者如何适应他们的癌症可能有助于医疗保健团队提供个性化的自我管理技能，以在整个癌症生存期间提高 QoL 并减轻症状负担。
