University of Miami.
Emory University.
Oncol Nurs Forum. 2022 Aug 18;49(5):421-431. doi: 10.1188/22.ONF.421-431.
To examine colorectal cancer (CRC) survivors' symptom characteristics (occurrence, frequency, and severity) during acute cancer survivorship.
PARTICIPANTS & SETTING: A cross-sectional study of 117 CRC survivors was conducted at a National Cancer Institute-designated cancer center in South Florida.
METHODS & VARIABLES: Symptom characteristics were assessed by the Therapy-Related Symptom Checklist. Participants completed a 25-item demographic questionnaire. Mann-Whitney U and Kruskal-Wallis H tests assessed between-group differences based on sex, age, education, and months since diagnosis. Exploratory factor analysis was performed to identify preliminary symptom clusters.
117 CRC survivors completed the study (age range = 21-88 years, 56% male, and 79% stage IV). Common symptoms included peripheral neuropathy, fatigue/feeling sluggish, and skin changes. Significance was found between months since diagnosis and number of symptoms (p = 0.03), suggesting that symptoms accumulate with time. Chemotherapy (85%) was the most common treatment type, and exploratory factor analysis identified two chemotherapy-related symptom clusters.
Nurses are poised to identify, prevent, and promote self-management skills to reduce symptoms.
探讨结直肠癌（CRC）幸存者在癌症急性康复期的症状特征（发生、频率和严重程度）。
在南佛罗里达州的一家美国国立癌症研究所指定的癌症中心进行了一项 117 例 CRC 幸存者的横断面研究。
症状特征采用治疗相关症状清单进行评估。参与者完成了一份 25 项的人口统计学问卷。根据性别、年龄、教育程度和诊断后月数，采用曼-惠特尼 U 检验和克鲁斯卡尔-沃利斯 H 检验评估组间差异。采用探索性因子分析来确定初步的症状群。
117 例 CRC 幸存者完成了研究（年龄范围为 21-88 岁，56%为男性，79%为 IV 期）。常见症状包括周围神经病变、疲劳/感觉迟钝和皮肤变化。诊断后月数与症状数量之间存在显著差异（p = 0.03），表明症状随时间积累。最常见的治疗类型是化疗（85%），探索性因子分析确定了两个与化疗相关的症状群。
护士有能力识别、预防和促进自我管理技能，以减轻症状。
