Hart D N, Fitzgerald P H, McKenzie J L, Walker R J, Fitzharris B M, Beard M E
N Z Med J. 1986 Nov 12;99(813):840-2.
A patient presented with superior vena caval obstruction caused by a tumour which resembled carcinoma of the lung both clinically and histologically. However, immunologic and cytogenetic analyses carried out on the mediastinal biopsy and on pleural fluid revealed that the tumour was of B cell origin, Burkitt-like in sub-type, and had the t(8;14) translocation. The nature of many poorly differentiated tumours may be more clearly identified with the help of immunological and cytogenetic analyses.
一名患者因肿瘤导致上腔静脉阻塞，该肿瘤在临床和组织学上均类似于肺癌。然而，对纵隔活检组织和胸腔积液进行的免疫和细胞遗传学分析显示，该肿瘤起源于B细胞，亚型为伯基特样，且存在t(8;14)易位。借助免疫和细胞遗传学分析，许多低分化肿瘤的性质可能会更清晰地得以确定。
