Department of Rehabilitation, Longyan First Affiliated Hospital of Fujian Medical University, Longyan 364000, China.
Department of Rehabilitation, Longyan First Hospital, Longyan 364000, China.
J Healthc Eng. 2022 Mar 26;2022:2545762. doi: 10.1155/2022/2545762. eCollection 2022.
Stroke is a group of diseases caused by the sudden rupture or blockage of blood vessels in the brain that prevent blood from flowing into the brain, resulting in brain tissue damage and dysfunction. Stroke has the characteristics of high morbidity, high disability, and high mortality. To investigate the effect of multidirectional transcranial direct current stimulation (tDCS) of the prefrontal lobe in stroke memory disorder. We evaluated 60 patients with poststroke memory impairment who underwent magnetic resonance diffusion tensor imaging (DTI) during their admission to our hospital between January 2018 and December 2020. The patients were divided into the prefrontal group ( = 15), dorsolateral group ( = 15), prefrontal + dorsolateral group ( = 15), and pseudostimulation group ( = 15). Assessments using the Rivermead Behavioral Memory Test (RBMT), Montreal Cognitive Assessment Scale (MoCA), Lovingston Occupational Therapy Cognitive Scale (LOTCA), and frontal lobe fractional anisotropy (FA) were performed before and after treatment. The RBMT, MoCA, and LOTCA scores in the prefrontal + dorsolateral group were significantly higher than those in the dorsolateral, prefrontal, and sham groups (all < 0.05). The posttreatment FA value of the frontal lobe was significantly higher in the prefrontal + dorsolateral group than in the dorsolateral, prefrontal, and sham stimulation groups (all < 0.05). The FA value of the frontal lobe was significantly lower in patients with severe memory impairment than in patients with mild-moderate memory impairment ( < 0.05). The area under the receiver operating characteristic curve was 0.801 (95% CI: 0.678-0.925, < 0.05), and the optimal cut-off value was 0.34, with a sensitivity and specificity of 81.60% and 72.70%, respectively. Prefrontal lobe + dorsolateral tDCS is beneficial in the treatment of post-stroke memory impairment. The DTI FA value can be useful in determining the degree of memory impairment.
中风是一组由脑血管突然破裂或阻塞引起的疾病，导致血液无法流入大脑，从而导致脑组织损伤和功能障碍。中风具有高发病率、高致残率和高死亡率的特点。本研究旨在探讨多方向经颅直流电刺激（tDCS）对中风后记忆障碍的影响。我们评估了 2018 年 1 月至 2020 年 12 月期间在我院住院期间接受磁共振弥散张量成像（DTI）检查的 60 例中风后记忆障碍患者。将患者分为前额叶组（n=15）、背外侧组（n=15）、前额叶+背外侧组（n=15）和假刺激组（n=15）。治疗前后采用Rivermead 行为记忆测试（RBMT）、蒙特利尔认知评估量表（MoCA）、Lovingston 职业治疗认知量表（LOTCA）和额叶分数各向异性（FA）进行评估。前额叶+背外侧组的 RBMT、MoCA 和 LOTCA 评分明显高于背外侧组、前额叶组和假刺激组（均<0.05）。前额叶+背外侧组治疗后的额叶 FA 值明显高于背外侧组、前额叶组和假刺激组（均<0.05）。严重记忆障碍患者的额叶 FA 值明显低于轻度至中度记忆障碍患者（<0.05）。受试者工作特征曲线下面积为 0.801（95%CI：0.678-0.925，<0.05），最佳截断值为 0.34，灵敏度和特异度分别为 81.60%和 72.70%。前额叶+背外侧 tDCS 对中风后记忆障碍有治疗作用。DTI FA 值可用于判断记忆障碍程度。
