Razafindrazoto Chantelli Iamblaudiot, Hasina Laingonirina Domoina Harivonjy, Ralaizanaka Behoavy Mahafaly, Randriamifidy Nitah Harivony, Rakotomaharo Mialitiana, Randrianiaina Antsa Fihobiana, Rakotoniaina Henintsoa, Maherison Sonny, Rakotomalala Jolivet Auguste, Rasolonjatovo Anjaramalala Sitraka, Rakotozafindrabe Andry Lalaina Rinà, Rabenjanahary Tovo Harimanana, Razafimahefa Soloniaina Hélio, Ramanampamonjy Rado Manitrala
Unity of Gastroenterology, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar.
Unity of Hepato-Gastroenterology, University Hospital Andrainjato, Fianarantsoa, Madagascar.
Int Med Case Rep J. 2022 Mar 29;15:125-134. doi: 10.2147/IMCRJ.S355276. eCollection 2022.
SARS-CoV-2 has been described as a respiratory tropic virus since its emergence in December 2019. During the course of the disease, other extra-pulmonary manifestations have been reported in the literature including pancreatic involvement such as acute pancreatitis. This phenomenon linking COVID-19 and acute pancreatitis has been reported by several case reports and cohort studies. No cases had been reported in sub-Saharan Africa and Madagascar. We report one more case Of COVID-19 induced acute pancreatitis in a Malagasy woman patient without risk factors, further consolidating the existing evidence.
A 44-year-old woman was diagnosed with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection and had a favorable course under home isolation and drug treatments. One week later, the patient was admitted to hospital with severe acute abdominal pain. Acute pancreatitis was considered according to the revised Atlanta criteria with the presence of the three criteria. Other etiologies of acute pancreatitis (lithiasis, alcohol, hypercalcemia, hypertriglyceridemia, tumor, trauma, surgery) were excluded. Ultimately, a COVID-19 induced acute pancreatitis was retained. The outcome was favorable under symptomatic medical treatment (fluid resuscitation, bowel rest, management of pain and vomiting, and early oral feeding). The patient was discharged after one week of hospitalization.
COVID-19 is a possible etiology of acute pancreatitis. Acute pancreatitis should be routinely ruled out in a patient with COVID-19 infection with acute abdominal pain.
自2019年12月出现以来，严重急性呼吸综合征冠状病毒2（SARS-CoV-2）一直被描述为一种呼吸道嗜性病毒。在疾病过程中，文献中还报道了其他肺外表现，包括胰腺受累，如急性胰腺炎。一些病例报告和队列研究报告了这种将2019冠状病毒病（COVID-19）与急性胰腺炎联系起来的现象。撒哈拉以南非洲和马达加斯加尚未报告过此类病例。我们报告了另一例无危险因素的马达加斯加女性患者因COVID-19诱发急性胰腺炎的病例，进一步巩固了现有证据。
一名44岁女性被诊断为感染严重急性呼吸综合征冠状病毒2（SARS-CoV-2），在居家隔离和药物治疗下病情好转。一周后，患者因严重急性腹痛入院。根据修订的亚特兰大标准，由于存在三条标准，考虑为急性胰腺炎。排除了急性胰腺炎的其他病因（结石、酒精、高钙血症、高甘油三酯血症、肿瘤、创伤、手术）。最终，确诊为COVID-19诱发的急性胰腺炎。在对症治疗（液体复苏、肠道休息、疼痛和呕吐管理以及早期经口喂养）下，预后良好。患者住院一周后出院。
COVID-19是急性胰腺炎的一种可能病因。对于有急性腹痛的COVID-19感染患者，应常规排除急性胰腺炎。
