Sudarsanam Hemanth, Ethiraj Dillibabu, Govarthanan Navaneetha Kumar, Kalyanasundaram Srinivasan, Chitra Sathya Arunachalam, Mohan Saisurendar
Department of Radio-diagnosis, Dr. Rela Institute and Medical Centre, Chennai, India.
Department of Critical Care Medicine, Dr. Rela Institute and Medical Centre, Chennai, India.
Oman Med J. 2021 Sep 30;36(5):e304. doi: 10.5001/omj.2021.129. eCollection 2021 Sep.
Coronaviruses are a large family of single-stranded RNA viruses infecting humans and animals, causing a multitude of symptoms. COVID-19 is not only known to affect the respiratory system, but shows unusual gastrointestinal complications. Pancreatitis can be caused by biliary stones, alcohol abuse, viruses, drug intake, metabolic syndromes, or trauma. Diagnosis of acute pancreatitis requires any two of the three criteria: acute onset of severe upper abdominal pain, consistent with pancreatitis; elevation of serum amylase or lipase, three times the upper limit of normal; and/or characteristic imaging findings. COVID-19 associated pancreatitis is thought to be mediated by the angiotensin-converting enzyme-2 receptor on the host cells, which are highly expressed in the pancreatic cells. Here, we report a unique case of acute necrotizing pancreatitis caused by COVID-19 with hyperglycemia and normal amylase and lipase levels.
冠状病毒是一大类感染人类和动物的单链RNA病毒，可引发多种症状。已知新冠病毒不仅会影响呼吸系统，还会出现异常的胃肠道并发症。胰腺炎可由胆结石、酗酒、病毒、药物摄入、代谢综合征或外伤引起。急性胰腺炎的诊断需要满足以下三项标准中的任意两项：严重上腹部疼痛急性发作，符合胰腺炎表现；血清淀粉酶或脂肪酶升高，超过正常上限的三倍；和/或特征性影像学表现。新冠病毒相关胰腺炎被认为是由宿主细胞上的血管紧张素转换酶2受体介导的，该受体在胰腺细胞中高度表达。在此，我们报告一例由新冠病毒引起的急性坏死性胰腺炎的独特病例，该病例伴有高血糖，淀粉酶和脂肪酶水平正常。
