Loesch Regina Becker Reifschneider, Ribeiro Rafaela M, Conceição Cláudia
Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL, Lisboa, Portugal
Global Health and Tropical Medicine, GHTM, Instituto de Higiene e Medicina Tropical, IHMT, Universidade Nova de Lisboa, UNL, Lisboa, Portugal.
BMJ Open. 2022 Apr 4;12(4):e056761. doi: 10.1136/bmjopen-2021-056761.
The contact investigation of tuberculosis (TB) index case is one of the critical elements pointed by the WHO to reach the end of the TB epidemic. The scoping review aimed to map out the recommended and the adopted processes applied to active contact investigation of TB index case in African Portuguese-speaking countries (PALOP).
Scoping review.
We searched B-on, Cochrane Library, PubMed, Web of Science, Scopus, WHOLIS, IRIS, OKR, each country's Ministry of Health websites, WHO, Global Fund, World Bank and bibliographic reference lists from February to May 2020.
All available literature on TB contact investigation in each country part of PALOP (Angola, Cape Verde, Guinea-Bissau, Mozambique and Sao Tome and Principe) published from 1 January 2010 to 31 January2020.
A data-charting form was developed to extract data on documents' characteristics and variables pertinent to the TB contact investigation process. Before qualitative analysis, we thematically synthesised findings and converted them into appropriate text units.
Fifteen documents were included in the scoping review. The recommended processes for TB contact investigation were identified only for Cape Verde and Mozambique. It included clinical evaluation, counselling and testing for HIV, chest radiography, tuberculin skin test, sputum smear microscopy or Xpert MTB/RIF. The adopted processes were detected only in research studies from Angola, Guinea-Bissau and Mozambique. Therefore, they cannot be assumed as adopted within the scope of the national programmes of the respective countries.
This review highlights the scarcity of references on TB contact investigation in PALOP at the End TB Strategy era. Furthermore, it is well clear the importance of an information system that provides actual data for assessing the real impact of such interventions in controlling the disease in African Portuguese-speaking countries.
结核病（TB）索引病例的接触者调查是世界卫生组织指出的实现结核病流行终结的关键要素之一。本范围综述旨在梳理出适用于非洲葡语国家（PALOP）结核病索引病例主动接触者调查的推荐流程和实际采用的流程。
范围综述。
我们于2020年2月至5月在B-on、考科蓝图书馆、PubMed、科学网、Scopus、WHOLIS、IRIS、OKR、各国卫生部网站、世界卫生组织、全球基金、世界银行以及文献参考文献列表中进行了检索。
2010年1月1日至2020年1月31日期间在PALOP每个国家（安哥拉、佛得角、几内亚比绍、莫桑比克以及圣多美和普林西比）发表的所有关于结核病接触者调查的现有文献。
制定了一份数据图表形式，以提取有关文献特征以及与结核病接触者调查过程相关变量的数据。在进行定性分析之前，我们对研究结果进行了主题综合，并将其转化为适当的文本单元。
范围综述纳入了15份文献。仅为佛得角和莫桑比克确定了结核病接触者调查的推荐流程。其中包括临床评估、HIV咨询与检测、胸部X光检查、结核菌素皮肤试验、痰涂片显微镜检查或Xpert MTB/RIF检测。仅在安哥拉、几内亚比绍和莫桑比克的研究中发现了实际采用的流程。因此，不能认为这些流程在各自国家的国家项目范围内得到了采用。
本综述凸显了在结核病流行终结战略时代，PALOP地区关于结核病接触者调查的参考文献稀缺。此外，很明显需要一个信息系统来提供实际数据，以评估此类干预措施在非洲葡语国家控制疾病方面的实际影响。
