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一份节段性睾丸梗死导致急性睾丸痛的病例报告。

A case report of acute testicular pain secondary to segmental testicular infarction.

机构信息

Department of Urology, The Second Affiliated Hospital of Soochow University, 1055 Sanxiang Rd, Suzhou, 215004, China.

出版信息

BMC Urol. 2022 Apr 5;22(1):52. doi: 10.1186/s12894-022-01006-7.

DOI:10.1186/s12894-022-01006-7
PMID:35382805
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8985257/
Abstract

BACKGROUND

Segmental testicular infarction is a rare condition that often occurs in the upper pole of the left testicle and usually presents with acute onset of scrotal pain. Contrast-enhanced ultrasound and MR are essential for diagnosing and differentiating segmental testicular infarction in clinical practice, and conservative treatment can only be adopted after a definitive diagnosis. In the present case, after conservative treatment, the infarct volume was reduced, the blood flow around the infarct was increased, and blood flow signals appeared in the infarct. We performed a correlation analysis to investigate the causes of these changes.

CASE PRESENTATION

A 33-year-old male, without any specific disease history, was admitted to the hospital with a 5-day history of left testicular pain, and the imaging showed focal necrosis of the left testicle with hemorrhage. He was diagnosed with segmental testicular infarction after differentiating and excluding it from malignant tumors. Conservative medical treatment was given, and the symptoms of testicular pain were relieved after treatment. After discharge, regular reexamination at follow-ups showed that the infarct's size was reduced, the blood flow around the infarct was increased, and blood flow signals appeared in the infarct.

CONCLUSION

Conservative treatment has become the standard treatment currently adopted after confirming the diagnosis of segmental testicular infarction through contrast-enhanced ultrasound and MR. The blood flow changes in and around the focus of testicular infarction can be related to various factors. At present, relevant conclusions of the underlying mechanisms were mainly deduced from infarction studies of other related organs such as the heart and brain; thus, the specific pathological mechanism needs further experimental verification.

摘要

背景

节段性睾丸梗死是一种罕见的疾病,通常发生在左侧睾丸的上极,且常表现为突发性阴囊疼痛。在临床实践中,对比增强超声和磁共振成像对于诊断和鉴别节段性睾丸梗死至关重要,且只有在明确诊断后才能采用保守治疗。在本病例中,经保守治疗后,梗死体积缩小,梗死周围血流增加,梗死区内出现血流信号。我们进行了相关性分析,以探讨这些变化的原因。

病例介绍

一名 33 岁男性,无特殊病史,因左侧睾丸疼痛 5 天入院,影像学表现为左侧睾丸局灶性坏死伴出血。经鉴别诊断排除恶性肿瘤后,诊断为节段性睾丸梗死。给予保守治疗,睾丸疼痛症状缓解后出院。出院后定期复查,发现梗死体积缩小,梗死周围血流增加,梗死区内出现血流信号。

结论

目前,通过对比增强超声和磁共振成像明确诊断节段性睾丸梗死后,通常采用保守治疗。睾丸梗死灶及其周围的血流变化可能与多种因素有关。目前,相关机制的潜在结论主要是从心脏和大脑等其他相关器官的梗死研究中推断出来的;因此,具体的病理机制需要进一步的实验验证。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b983/8985257/3da892438346/12894_2022_1006_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b983/8985257/143e77f33d8e/12894_2022_1006_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b983/8985257/827a3be5c5f1/12894_2022_1006_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b983/8985257/3da892438346/12894_2022_1006_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b983/8985257/143e77f33d8e/12894_2022_1006_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b983/8985257/827a3be5c5f1/12894_2022_1006_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b983/8985257/3da892438346/12894_2022_1006_Fig3_HTML.jpg

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Experimental ischaemia-reperfusion injury induces vascular endothelial growth factor expression in the rat testis.实验性缺血再灌注损伤诱导大鼠睾丸中血管内皮生长因子的表达。
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