Bazarbashi Shouki, Alkhaldi Turkiah, Aseafan Mohamed, Melaibari Maryam, Almuhisen Sara, Alharbi Samar, Alghabban Abdulrahman, Aljumaa Jihad, Eldali Abdelmoneim, Maraiki Fatma, Owaidah Tarek, Alzahrani Hazzaa
Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, SAU.
Pharmacy services, King Fahad Medical City, Riyadh, SAU.
Cureus. 2022 Mar 29;14(3):e23624. doi: 10.7759/cureus.23624. eCollection 2022 Mar.
The relationship between cancers and thromboembolic events is well established. In our study, we aim to determine the burden of thromboembolic events in patients with solid tumors and identify the risk factors related to their development.
MATERIALS & METHODS: Data on patients with solid tumors and thromboembolism between January 2013 and September 2014 were collected and analyzed.
During the study period 174 patients were identified. Of which, 172 (98.9%) had venous thrombus embolism, 137 (79%) were diagnosed with deep vein thromboses, 67 (38.5%) with pulmonary embolism, 84 (48.3%) were symptomatic and 90 (51.7) were incidental at diagnosis. The most common patients and disease characteristics were female sex, high body mass index (BMI), metastatic stage, colorectal and breast primaries, and anti-neoplastic therapy.
Our study confirmed the high burden of thromboembolic events in cancer patients and the relevant factors associated with its development.
癌症与血栓栓塞事件之间的关系已得到充分证实。在我们的研究中，我们旨在确定实体瘤患者血栓栓塞事件的负担，并确定与其发生相关的风险因素。
收集并分析了2013年1月至2014年9月期间实体瘤和血栓栓塞患者的数据。
在研究期间共识别出174例患者。其中，172例（98.9%）发生静脉血栓栓塞，137例（79%）被诊断为深静脉血栓形成，67例（38.5%）发生肺栓塞，84例（48.3%）有症状，90例（51.7%）在诊断时为偶然发现。最常见的患者和疾病特征为女性、高体重指数（BMI）、转移期、结直肠癌和乳腺癌原发肿瘤以及抗肿瘤治疗。
我们的研究证实了癌症患者血栓栓塞事件的高负担以及与其发生相关的因素。
