超声在系统性硬化症中的作用：引领临床与研究进展的前沿力量。
The role of ultrasound in systemic sclerosis: On the cutting edge to foster clinical and research advancement.
作者信息
Hughes Michael, Bruni Cosimo, Cuomo Giovanna, Delle Sedie Andrea, Gargani Luna, Gutierrez Marwin, Lepri Gemma, Ruaro Barbara, Santiago Tania, Suliman Yossra, Watanabe Shinji, Iagnocco Annamaria, Furst Daniel, Bellando-Randone Silvia
机构信息
Department of Rheumatology, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK.
Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
出版信息
J Scleroderma Relat Disord. 2021 Jun;6(2):123-132. doi: 10.1177/2397198320970394. Epub 2020 Nov 19.
Abstract
Ultrasound has been widely explored in systemic sclerosis in the clinical and research settings. Ultrasound allows a non-invasive and ionising radiation-free 'window' into this complex disease and is well-suited to repeated examinations. Ultrasound provides novel insights into the pathogenesis and measurement of disease in systemic sclerosis, including early (preclinical) internal organ involvement. The purpose of this review is to describe the role of ultrasound to foster clinical and research advancements in systemic sclerosis relating to (1) musculoskeletal, (2) digital ulcer, (3) lung disease and (4) skin disease. We also highlight unmet needs which much be addressed for ultrasound to assume a central role in systemic sclerosis clinical care and research.
摘要
在临床和研究领域，超声已在系统性硬化症中得到广泛探索。超声为深入了解这种复杂疾病提供了一个无创且无电离辐射的“窗口”，非常适合进行反复检查。超声为系统性硬化症的发病机制和疾病测量提供了新的见解，包括早期（临床前）内脏器官受累情况。本综述的目的是描述超声在促进系统性硬化症临床和研究进展方面的作用，涉及（1）肌肉骨骼、（2）指端溃疡、（3）肺部疾病和（4）皮肤疾病。我们还强调了一些尚未满足的需求，为使超声在系统性硬化症临床护理和研究中发挥核心作用，这些需求必须得到解决。
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