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纤维腺瘤内原位导管癌:一例病例报告及文献复习

Ductal carcinoma in situ within a fibroadenoma: A case report and review of literature.

作者信息

Olivares-Antúnez Yazmin, Dávila-Zablah Yesika Janett, Vázquez-Ávila José Raúl, Gómez-Macías Gabriela Sofía, Mireles-Aguilar María Teresa, Garza-Montemayor Margarita Lilia

机构信息

Department of Diagnostic Breast Imaging Center, Hospital Zambrano Hellion, Tecnológico de Monterrey, Nuevo León 66260, Mexico.

Department of Patology Service, Hospital San José, Tecnológico de Monterrey, Nuevo León 64710, Mexico.

出版信息

World J Radiol. 2024 Mar 28;16(3):58-68. doi: 10.4329/wjr.v16.i3.58.

Abstract

BACKGROUND

Fibroadenoma (FA) is the most common tumor found in young women, although it can occur in any age group. Ductal carcinoma in situ (DCIS) that is confined in a FA is rare; it is most frequently reported as an incidental finding.

CASE SUMMARY

We report a case of DCIS within a FA in a 46-year-old female without cancer-related personal and family histories. The patient was diagnosed with a breast conglomerate of nodules and was followed for 1 year. In the current control image study, we found suspicious microcalcification, as a new finding, within one of the nodules. Consequently, a core biopsy of the tumor, which appeared hypoechoic, oval, and circumscribed, was performed. The pathological diagnosis was ductal carcinoma in situ within a fibroepithelial lesion. The patient underwent breast-conserving surgery and received radiotherapy as well as endocrine therapy (tamoxifen).

CONCLUSION

We recommend a multidisciplinary approach for adequate treatment and follow-up.

摘要

背景

纤维腺瘤(FA)是年轻女性中最常见的肿瘤,不过它可发生于任何年龄组。局限于纤维腺瘤内的导管原位癌(DCIS)很罕见;它最常作为偶然发现被报道。

病例摘要

我们报告一例46岁女性的纤维腺瘤内导管原位癌,该患者无癌症相关个人史和家族史。患者被诊断为乳腺结节性肿物并随访1年。在此次对照影像学检查中,我们在其中一个结节内发现了可疑微钙化这一新发现。因此,对表现为低回声、椭圆形且边界清晰的肿瘤进行了粗针活检。病理诊断为纤维上皮性病变内的导管原位癌。患者接受了保乳手术,并接受了放疗以及内分泌治疗(他莫昔芬)。

结论

我们建议采用多学科方法进行充分的治疗和随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6aaf/10999957/50c823e63641/WJR-16-58-g001.jpg

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