Nawaz Shahid, Saleem Maira
Institute of Microbiology and Molecular Genetics, University of the Punjab, Lahore, Pakistan.
Infect Disord Drug Targets. 2022;22(7):7-13. doi: 10.2174/1871526522666220407001744.
Since the advent of the COVID-19 pandemic in 2019, a mammoth research activity targeting the etiological features of COVID-19 has commenced. Many aspects of the disease have been studied, and various others are under consideration. The secondary microbial coinfections with COVID-19 have generated some serious concerns across the globe. This review mainly focuses on the notable secondary coinfections. The coinfection of influenza, tuberculosis, and typhoid may mimic the original COVID-19 symptoms. Physicians and clinicians must focus on the secondary coinfections which may aggravate the disease progression towards acute respiratory disorder syndrome (ARDS). Diagnostic strategies must also be redefined to determine the actual underlying secondary coinfection. There is a need for combination therapy and diagnostic approaches to minimize the risks associated with the COVID-19 pandemic effectively.
自2019年新冠疫情出现以来,针对新冠病毒病因特征的大规模研究活动已经展开。该疾病的许多方面都已得到研究,还有其他诸多方面正在研究之中。新冠病毒的继发性微生物合并感染已在全球引发了一些严重担忧。本综述主要关注显著的继发性合并感染。流感、结核病和伤寒的合并感染可能会模仿最初的新冠症状。医生和临床医生必须关注可能会使疾病向急性呼吸窘迫综合征(ARDS)进展加剧的继发性合并感染。还必须重新定义诊断策略,以确定实际潜在的继发性合并感染。需要采用联合治疗和诊断方法,以有效降低与新冠疫情相关的风险。