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谁有肾损伤后死亡的风险?1799 例肾损伤后 30 天死亡率的分析。

Who Is at Risk of Death after Renal Trauma? An Analysis of Thirty-Day Mortality after 1,799 Cases of Renal Trauma.

机构信息

Department of Urology and Kidney Transplantation, Aix-Marseille University, APHM, Conception Academic Hospital, Marseille, France.

Department of Urology, University of Paris Sud, CHU Bicetre, Paris, France.

出版信息

Urol Int. 2023;107(2):165-170. doi: 10.1159/000521554. Epub 2022 Apr 7.

Abstract

INTRODUCTION

The aim of the study was to report the 30-day mortality (30DM) after renal trauma and identify the risk factors associated with death.

METHODS

The TRAUMAFUF project was a retrospective multi-institutional study including all patients with renal trauma admitted to 17 French hospitals between 2005 and 2015. The included population focused on patients of all age groups who underwent renal trauma during the study period. The primary outcome was death within 30 days following trauma. The multivariate logistic regression model with a stepwise backward elimination was used to identify predictive factors of 30DM.

RESULTS

Data on 1,799 renal trauma were recorded over the 10-year period. There were 59 deaths within 30 days of renal trauma, conferring a 30DM rate of 3.27%. Renal trauma was directly involved in 5 deaths (8.5% of all deaths, 0.3% of all renal trauma). Multivariate stepwise logistic regression analysis revealed that age >40 years (odds ratio [OR] 2.18; 95% confidence interval [CI]: 1.20-3.99; p = 0.01), hemodynamic instability (OR 4.67; 95% CI: 2.49-9; p < 0.001), anemia (OR 3.89; 95% CI: 1.94-8.37; p < 0.001), bilateral renal trauma (OR 6.77; 95% CI: 2.83-15.61; p < 0.001), arterial contrast extravasation (OR 2.09; 95% CI: 1.09-3.96; p = 0.02), and concomitant visceral and bone injuries (OR 6.57; 95% CI: 2.41-23.14; p < 0.001) were independent predictors of 30DM.

CONCLUSION

Our large multi-institutional study supports that the 30DM of 3.27% after renal trauma is due to the high degree of associated injuries and was rarely a consequence of renal trauma alone. Age >40 years, hemodynamic instability, anemia, bilateral renal trauma, arterial contrast extravasation, and concomitant visceral and bone lesions were predictors of death. These results can help clinicians to identify high-risk patients.

摘要

简介

本研究旨在报告肾损伤后 30 天死亡率(30DM),并确定与死亡相关的风险因素。

方法

TRAUMAFUF 项目是一项回顾性多机构研究,纳入了 2005 年至 2015 年间法国 17 家医院收治的所有肾损伤患者。该研究人群包括所有年龄段的患者,这些患者在研究期间均经历了肾损伤。主要结局是创伤后 30 天内死亡。采用逐步后退消除的多变量逻辑回归模型来确定 30DM 的预测因素。

结果

在 10 年期间记录了 1799 例肾损伤数据。肾损伤后 30 天内有 59 例死亡,30DM 发生率为 3.27%。肾损伤直接导致 5 例死亡(所有死亡的 8.5%,所有肾损伤的 0.3%)。多变量逐步逻辑回归分析显示,年龄>40 岁(比值比[OR] 2.18;95%置信区间[CI]:1.20-3.99;p = 0.01)、血流动力学不稳定(OR 4.67;95%CI:2.49-9;p<0.001)、贫血(OR 3.89;95%CI:1.94-8.37;p<0.001)、双侧肾损伤(OR 6.77;95%CI:2.83-15.61;p<0.001)、动脉造影剂外渗(OR 2.09;95%CI:1.09-3.96;p = 0.02)和同时存在的内脏和骨损伤(OR 6.57;95%CI:2.41-23.14;p<0.001)是 30DM 的独立预测因素。

结论

我们的大型多机构研究支持肾损伤后 30DM 为 3.27%,这是由于相关损伤程度高,很少是单纯肾损伤的结果。年龄>40 岁、血流动力学不稳定、贫血、双侧肾损伤、动脉造影剂外渗和同时存在的内脏和骨损伤是死亡的预测因素。这些结果可以帮助临床医生识别高危患者。

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