Owen H, Glavin R J, Shaw N A
Br J Anaesth. 1986 Dec;58(12):1371-5. doi: 10.1093/bja/58.12.1371.
The effect of the regular administration of ibuprofen on pain following abdominal surgery was investigated in a double-blind placebo-controlled study. The analgesic action of ibuprofen was measured by a reduction in the amount of morphine self-administered from an On-Demand Analgesic Computer. Pain scores, nausea scores and blood loss were similar in both groups, but patients receiving ibuprofen demanded significantly less morphine in the 24 h after surgery.