Bachelor of Public Health Program, School of Health and Allied Sciences, Pokhara University, Pokhara, Nepal.
School of Health and Allied Sciences, Pokhara University, Pokhara, Nepal.
PLoS One. 2022 Apr 8;17(4):e0266661. doi: 10.1371/journal.pone.0266661. eCollection 2022.
Nicotine dependence is an addiction to tobacco products caused by the chemical nicotine present in tobacco. 80% of premature deaths due to nicotine dependence come from low-and middle-income countries. Since most of the public health studies have focused solely on psychological and behavioral factors associated with tobacco smoking, this study aims to assess the nicotine dependence and stages of change of quitting smoking.
A community based quantitative cross-sectional study was conducted among 280 smokers aged 15-69 years in Bharatpur metropolitan, Nepal. A semi-structured and validated questionnaire was used during the face-to-face interviews. Nicotine dependence among participants was assessed using the six-item Fagerstrom Test for Nicotine Dependence (FTND). Chi-square test and multivariate logistic regression analysis were performed to assess the associations between variables at the significance level α = 0.05.
In the study population, the mean score of FTND was 5.15 ± 2.34. 33.9% participants had a high level of nicotine dependence and nearly half of the participants felt difficulty to refrain smoking even in No-smoking areas. Almost three out of ten respondents were prepared for smoking cessation. It was found that age group 20-39 years were more likely to have nicotine dependence (AOR 3.308, 95% CI = 1.039-10.534), those who initiated smoking before age of 15 were associated with a greater risk of nicotine dependence (AOR 3.68, 95% CI = 1.826-7.446), participants spending more on tobacco products (more than Rs 2400 monthly) were associated with an increased risk of nicotine dependence (AOR 4.47, 95% CI = 2.225-8.991), those who initiated smoking due to mental stress were more likely to have nicotine addiction (AOR 2.522, 95% CI = 1.004-6.028), and those who had no thought of quitting smoking were more associated with nicotine dependence (AOR 4.935, 95% CI = 1.458-16.699).
Our study showed that high level of nicotine dependence is a major public health problem in low-and middle-income countries like Nepal. It also highlights that effective smoking cessation programs should be developed considering the level of nicotine dependence with more focus on early interventions of its associated factors.
尼古丁依赖是一种对烟草制品中化学物质尼古丁上瘾的疾病,80%因尼古丁依赖导致的过早死亡发生在中低收入国家。由于大多数公共卫生研究仅关注与吸烟相关的心理和行为因素,因此本研究旨在评估尼古丁依赖和戒烟阶段的变化。
在尼泊尔 Bharatpur 大都市进行了一项基于社区的定量横断面研究,共纳入 280 名年龄在 15-69 岁的吸烟者。在面对面访谈中使用了半结构式和经过验证的问卷。使用六分量表 Fagerstrom 尼古丁依赖测试(FTND)评估参与者的尼古丁依赖程度。采用卡方检验和多变量逻辑回归分析,在显著性水平α=0.05 下评估变量之间的关联。
在研究人群中,FTND 的平均得分为 5.15±2.34。33.9%的参与者有较高的尼古丁依赖程度,近一半的参与者即使在禁烟区也难以抑制吸烟。近十分之三的受访者准备戒烟。结果发现,20-39 岁年龄组更有可能出现尼古丁依赖(OR3.308,95%CI=1.039-10.534),15 岁前开始吸烟的参与者与更大的尼古丁依赖风险相关(OR3.68,95%CI=1.826-7.446),每月花在烟草产品上的钱超过 2400 卢比(OR4.47,95%CI=2.225-8.991)的参与者与尼古丁依赖风险增加相关,因精神压力而开始吸烟的参与者更有可能上瘾(OR2.522,95%CI=1.004-6.028),而没有戒烟想法的参与者更有可能依赖尼古丁(OR4.935,95%CI=1.458-16.699)。
我们的研究表明,高尼古丁依赖是尼泊尔等中低收入国家的一个主要公共卫生问题。它还强调,应该制定有效的戒烟计划,考虑到尼古丁依赖的程度,并更加注重其相关因素的早期干预。