David Geffen School of Medicine, UCLA, Department of Neurology, Los Angeles, CA, United States; PADRECC, West Los Angeles, Veterans Administration, Los Angeles, CA, United States.
Spinal Cord Injury/Disorders Service, Veterans Administration Long Beach Healthcare System, Long Beach, CA, United States.
Int Rev Neurobiol. 2022;162:171-184. doi: 10.1016/bs.irn.2021.12.006. Epub 2022 Mar 15.
Nonmotor symptoms of Parkinson's disease (PD) range from neuropsychiatric and cognitive to sleep, sensory, and genito-urinary disorders, and occur as a result of the disease process as well as due to side effects of drug treatment for PD. Sexual dysfunction is an important aspect of the nonmotor profile of Parkinson's but is rarely discussed. Sexual health is considered an integral element of holistic health, thus sexual dysfunction can also significantly impact quality of life in people with Parkinson's. The effect of sexual dysfunction of PD, both disease related and drug induced, on the concept of "wellness" of patients and their intimate partners is poorly understood, inadequately researched and a key unmet need in care and support. In this chapter we discuss the concept of "wellness" as applied to the treatment of PD, the ways in which nonmotor symptoms and other aspects of living may affect wellness in PD, and strategies for addressing sexual health utilizing a wellness model.
帕金森病（PD）的非运动症状范围从神经精神和认知到睡眠、感觉和生殖泌尿系统障碍，这些症状是由于疾病过程以及 PD 药物治疗的副作用引起的。性功能障碍是帕金森病非运动特征的一个重要方面，但很少被讨论。性健康被认为是整体健康的一个组成部分，因此性功能障碍也会显著影响帕金森病患者的生活质量。PD 的性功能障碍，无论是与疾病相关还是与药物相关，对患者及其亲密伴侣的“健康”概念的影响，人们知之甚少，研究不足，这是护理和支持方面的一个关键未满足需求。在本章中，我们讨论了将“健康”概念应用于 PD 治疗的情况，讨论了非运动症状和生活的其他方面可能如何影响 PD 中的健康，以及利用健康模型解决性健康问题的策略。
