King's College London, Department of Neurosciences, Institute of Psychiatry, Psychology & Neuroscience, London, United Kingdom; Parkinson's Foundation Centre of Excellence, King's College Hospital, Denmark Hill, London, United Kingdom; Center for Neurodegenerative Diseases and the Aging Brain, Department of Clinical Research in Neurology, University of Bari 'Aldo Moro', "Pia Fondazione Cardinale G. Panico", Tricase, Lecce, Italy.
King's College London, Department of Neurosciences, Institute of Psychiatry, Psychology & Neuroscience, London, United Kingdom; Parkinson's Foundation Centre of Excellence, King's College Hospital, Denmark Hill, London, United Kingdom.
Int Rev Neurobiol. 2022;162:97-116. doi: 10.1016/bs.irn.2021.12.004. Epub 2022 Jan 21.
Sexual dysfunctions (SD) are frequent and highly disabling nonmotor manifestations of Parkinson's disease (PD) but are also potentially treatable. Neurologists should actively discuss, recognize and treat sexual health issues as an integral part of the management of the disease. In this chapter, we provide recommendations for managing and treating both primary and secondary SD in PD. Many sexual problems can be, at least partially, improved by adjusting the treatment of motor, nonmotor symptoms and comorbidities. Although some treatments of primary SD are evidence-based, many therapeutic options have not been yet systematically studied in patients with PD. The development of new treatments and repurposing of existing remedies in patients with PD remain an unmet need.
性功能障碍（SD）是帕金森病（PD）常见且高度致残的非运动表现，但也是潜在可治疗的。神经科医生应积极讨论、识别和治疗性功能健康问题，将其作为疾病管理的一个组成部分。在本章中，我们提供了管理和治疗 PD 中原发性和继发性 SD 的建议。许多性功能问题可以通过调整运动、非运动症状和合并症的治疗来至少部分改善。虽然一些原发性 SD 的治疗方法有循证医学证据，但许多治疗选择尚未在 PD 患者中进行系统研究。在 PD 患者中开发新的治疗方法和重新利用现有药物仍然是一个未满足的需求。
