Department of Chemistry, National Tsing Hua University, 101, Section 2, Kuang-Fu Rd., Hsinchu, 300044, Taiwan.
Department of Chemistry, National Tsing Hua University, 101, Section 2, Kuang-Fu Rd., Hsinchu, 300044, Taiwan; Department of Applied Chemistry, National Yang Ming Chiao Tung University, 1001 University Road, Hsinchu, 300093, Taiwan.
Anal Chim Acta. 2022 Apr 29;1204:339699. doi: 10.1016/j.aca.2022.339699. Epub 2022 Mar 15.
Fizzy extraction (FE) is a technique that utilizes effervescence phenomenon to extract volatile organic compounds (VOCs) from liquid matrices for subsequent analysis. To induce effervescence, a liquid sample is first pressurized (at ∼ 150 kPa) with an extractant gas (here, nitrogen), and then rapidly depressurized. In this work, we combine an in-house-built FE system with a commercial ion-mobility spectrometry (IMS) module in order to develop a portable analytical platform for in-situ analysis of VOCs in liquid samples. The size and shape of the FE-IMS platform are similar to those of a typical airline catering trolley. Its operation is enabled by several electronic and electromechanical components (a single-board computer, two microcontroller boards, a relay board, six DC-DC converters, a pressure regulator, a solenoid valve, and a pinch valve). The platform can carry out the extraction procedure as well as acquire, process, and transmit the data to a cloud-storage service. A custom-designed graphical user interface allows the user to select one of the available operation modes: full spectrum mode, ion current profile mode, and cleaning mode. The interface also allows one to follow the analysis progress, display the final result, and upload it to the Internet cloud. The platform has been characterized using three standards: ethyl acetate, ethyl propanoate, and butanone; and their limits of detection are 4.51 × 10 M, 2.74 × 10 M, and 1.26 × 10 M, respectively. Furthermore, its ability to analyze real samples (alcoholic and non-alcoholic beverages) has been demonstrated.
沸腾萃取（FE）是一种利用冒泡现象从液体基质中提取挥发性有机化合物（VOCs）以供后续分析的技术。为了引发冒泡，首先将液体样品用萃取剂气体（此处为氮气）加压（约 150kPa），然后迅速减压。在这项工作中，我们将自制的 FE 系统与商用离子迁移谱（IMS）模块相结合，以开发一种用于现场分析液体样品中 VOCs 的便携式分析平台。FE-IMS 平台的大小和形状类似于典型的航空配餐推车。它的操作由几个电子和机电组件（单板计算机、两个微控制器板、继电器板、六个 DC-DC 转换器、压力调节器、电磁阀和夹管阀）启用。该平台可以执行提取程序，以及采集、处理和将数据传输到云存储服务。一个定制的图形用户界面允许用户从可用的操作模式中选择一种：全谱模式、离子电流分布模式和清洗模式。该界面还允许用户跟踪分析进度、显示最终结果并将其上传到互联网云。该平台已经使用三种标准进行了表征：乙酸乙酯、丙酸乙酯和丁酮；它们的检测限分别为 4.51×10-6 M、2.74×10-6 M 和 1.26×10-6 M。此外，还展示了其分析实际样品（含酒精和不含酒精的饮料）的能力。
