MGH Alcohol Liver Center, Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
MGH Alcohol Liver Center, Gastrointestinal Unit, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
Clin Gastroenterol Hepatol. 2023 Jun;21(6):1646-1648. doi: 10.1016/j.cgh.2022.03.042. Epub 2022 Apr 8.
One of the most common and devastating complications of alcohol use disorder (AUD) is the development of alcohol-associated liver disease (ALD). Unfortunately, outcomes of patients with ALD are poor, in large part because patients with ALD are diagnosed at a much later stage of disease compared with patients with other causes of liver disease. Accordingly, earlier detection is critical in combating the high mortality associated with ALD. In this work, we sought to assess the feasibility and impact of evaluating high-risk patients with no prior documented liver disease for the presence of advanced ALD while admitted to the hospital.
酒精使用障碍(AUD)最常见和最具破坏性的并发症之一是酒精相关性肝病(ALD)的发展。不幸的是,ALD 患者的预后很差,很大程度上是因为与其他原因导致的肝病患者相比,ALD 患者在疾病的晚期才被诊断出来。因此,早期检测对于对抗与 ALD 相关的高死亡率至关重要。在这项工作中,我们试图评估在住院期间对没有既往记录的肝脏疾病的高危患者进行先进的 ALD 检测的可行性和影响。