Tecnologico de Monterrey, School of Engineering and Sciences, Mexico City, 14380, Mexico.
Tecnologico de Monterrey, School of Engineering and Sciences, Mexico City, 14380, Mexico.
Comput Biol Med. 2022 Jun;145:105479. doi: 10.1016/j.compbiomed.2022.105479. Epub 2022 Apr 2.
High blood pressure early screening remains a challenge due to the lack of symptoms associated with it. Accordingly, noninvasive methods based on photoplethysmography (PPG) or clinical data analysis and the training of machine learning techniques for hypertension detection have been proposed in the literature. Nevertheless, several challenges arise when analyzing PPG signals, such as the need for high-quality signals for morphological feature extraction from PPG related to high blood pressure. On the other hand, another popular approach is to use deep learning techniques to avoid the feature extraction process. Nonetheless, this method requires high computational power and behaves as a black-box approach, which impedes application in a medical context. In addition, considering only the socio-demographic and clinical data of the subject does not allow constant monitoring. This work proposes to use the wavelet scattering transform as a feature extraction technique to obtain features from PPG data and combine it with clinical data to detect early hypertension stages by applying Early and Late Fusion. This analysis showed that the PPG features derived from the wavelet scattering transform combined with a support vector machine can classify normotension and prehypertension with an accuracy of 71.42% and an F1-score of 76%. However, classifying normotension and prehypertension by considering both the features extracted from PPG signals through wavelet scattering transform and clinical variables such as age, body mass index, and heart rate by either Late Fusion or Early Fusion did not provide better performance than considering each data type separately in terms of accuracy and F1-score.
由于高血压缺乏相关症状,早期筛查仍然具有挑战性。因此,文献中提出了基于光电容积脉搏波(PPG)或临床数据分析和训练机器学习技术来检测高血压的非侵入性方法。然而,在分析 PPG 信号时会出现一些挑战,例如需要高质量的信号来提取与高血压相关的 PPG 的形态特征。另一方面,另一种流行的方法是使用深度学习技术来避免特征提取过程。然而,这种方法需要高计算能力,并且表现为黑盒方法,这阻碍了在医学环境中的应用。此外,仅考虑受试者的社会人口统计学和临床数据并不能进行持续监测。本工作提出使用小波散射变换作为特征提取技术,从 PPG 数据中获取特征,并结合临床数据,通过应用早期融合和晚期融合来检测早期高血压阶段。该分析表明,将小波散射变换衍生的 PPG 特征与支持向量机相结合,可以以 71.42%的准确率和 76%的 F1 分数对正常血压和前期高血压进行分类。然而,通过晚期融合或早期融合同时考虑通过小波散射变换从 PPG 信号中提取的特征以及年龄、体重指数和心率等临床变量来分类正常血压和前期高血压,在准确性和 F1 分数方面并不比分别考虑每种数据类型提供更好的性能。